Bagaria Vaibhav, Tiwari Anjali, Kini Abhishek, Lobo Gajiwala Astrid, Bhagunde Prasad, Dave Arpit
Department of Orthopedic Surgery, Sir H. N. Reliance Foundation Hospital and Research Centre, Girgaum, Mumbai, Maharashtra 400004 India.
Novo Tissue Bank and Research Centre, Sir H. N. Reliance Foundation Hospital and Research Centre, Girguam, Mumbai, India.
Indian J Orthop. 2022 Jul 2;56(9):1533-1546. doi: 10.1007/s43465-022-00661-0. eCollection 2022 Sep.
A tissue bank is an establishment that aids in retrieval, processing, storage, and distribution of human tissue for transplantation. For many years, such banks have been dispensing tissue to orthopaedic surgeons, performing reconstructive surgeries.
The retrieval, preparation, and delivery of musculoskeletal tissue used for transplantation is an intricate process involving varying practices among different musculoskeletal tissue banks.
Musculoskeletal allografts are used in various orthopaedic surgeries ranging from primary bone defects, trauma, and carcinoma to congenital disabilities. Every decade brings in paradigm shifts and new hope for treating challenging cases with the aid of newer devices and materials.
This review article outlines various technical, regulatory and quality enhancement steps involved in tissue banking. Also, it discusses the road ahead and the research avenues for developing novel allograft products with the synergy of tissue banks and clinicians.
The online version contains supplementary material available at 10.1007/s43465-022-00661-0.
组织库是一个协助获取、处理、储存和分发用于移植的人体组织的机构。多年来,此类库一直在向骨科医生提供组织,用于进行重建手术。
用于移植的肌肉骨骼组织的获取、制备和交付是一个复杂的过程,不同的肌肉骨骼组织库有不同的做法。
肌肉骨骼同种异体移植物用于各种骨科手术,范围从原发性骨缺损、创伤、癌症到先天性残疾。每十年都会带来范式转变,并借助更新的设备和材料为治疗具有挑战性的病例带来新希望。
这篇综述文章概述了组织库涉及的各种技术、监管和质量提升步骤。此外,它还讨论了未来的道路以及通过组织库和临床医生的协同作用开发新型同种异体移植产品的研究途径。
在线版本包含可在10.1007/s43465-022-00661-0获取的补充材料。