Wang Zeju, Sheng Xinru, Wu Yitao, Liu Yang, Zhu Huangtianzhi, Huang Feihe
Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou 311215, P. R. China.
ACS Appl Mater Interfaces. 2022 Sep 14;14(36):41072-41078. doi: 10.1021/acsami.2c11776. Epub 2022 Sep 2.
2,6-Lutidine () is a very important raw material in the chemical industry, but the impurities of 3-picoline () and 4-picoline () existing in seriously affect its quality. Considering different molecular sizes of these three compounds, herein, we exploit nonporous adaptive crystals (NACs) of pillararenes as purifying agents for removal of and in . We find that -ethylated pillar[5]arene () can selectively adsorb and , while negligible capture of is observed, resulting in improvement of the purity of up to 94.9%. Single-crystal structures indicate that the excellent selectivity originates from the size match and complexation stability differences among different host/guest pairs. After purification, NACs of can be easily regenerated and used in the next run without a significant performance degradation.
2,6-二甲基吡啶（ ）是化学工业中一种非常重要的原料，但 中存在的3-甲基吡啶（ ）和4-甲基吡啶（ ）杂质严重影响其质量。考虑到这三种化合物不同的分子大小，在此，我们利用柱芳烃的无孔自适应晶体（NACs）作为净化剂，用于去除 中的 和 。我们发现，乙基化柱[5]芳烃（ ）可以选择性地吸附 和 ，而对 的捕获量可忽略不计，从而使 的纯度提高到94.9%。单晶结构表明，优异的选择性源于不同主客体对之间的尺寸匹配和络合稳定性差异。纯化后， 的NACs可以很容易地再生，并用于下一轮操作，而不会有显著的性能下降。
