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442 例犬的延迟愈合、不愈合和愈合不良。

Delayed union, non-union and mal-union in 442 dogs.

机构信息

Small Animal Hospital, School of Veterinary Medicine, University of Glasgow, Glasgow, UK.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, California, USA.

出版信息

Vet Surg. 2022 Oct;51(7):1087-1095. doi: 10.1111/vsu.13880. Epub 2022 Aug 27.

Abstract

OBJECTIVES

(1) To estimate the prevalence of delayed union, non-union and mal-union in canine fractures; (2) to describe fracture, demographic, and treatment characteristics for these outcomes; (3) to identify risk factors for delayed or non-union.

STUDY DESIGN

Retrospective study.

SAMPLE POPULATION

Four hundred and forty two dogs (461 fractures).

METHODS

A review was conducted of clinical records and radiographs from 2 teaching hospitals. "Union," "delayed union," "non-union" and "mal-union" were defined, and fracture, demographic, treatment, and outcome variables described. Differences in proportions or medians between "union," "delayed union" and "non-union" were tested using χ and Mann-Whitney U-tests for categorical and continuous variables respectively. Potential explanatory variables for "delayed or non-union" were tested using logistic regression to identify risk factors.

RESULTS

Median radiographic follow up was 53 days (14-282). Delayed union occurred in 13.9% of fractures (64/461), non-union in 4.6% (21/461), and mal-union in 0.7% (3/461). Risk factors for delayed or non-union were age (OR 1.21, 95% CI 1.12-1.31); comminuted fracture (OR 4.24, 95% CI 2.4-7.5); treatment with bone graft (all types) (OR 3.32, 95% CI 1.3-8.5); surgical site infection (OR 3.24, 95% CI 1.17-8.97), and major implant failure (OR 12.94, 95% CI 5.06-33.1).

CONCLUSION

Older dogs, dogs with comminuted fractures, surgical site infection, or major implant failure were at increased odds of delayed or non-union. Radius and ulna fractures in toy breed dogs were not at increased odds of delayed or non-union.

CLINICAL SIGNIFICANCE

The identified risk factors should inform fracture planning and prognosticating. The prognosis for radial fractures in toy breeds appears better than historically believed.

摘要

目的

(1)评估犬骨折延迟愈合、不愈合和畸形愈合的发生率;(2)描述这些结果的骨折、人口统计学和治疗特征;(3)确定延迟或不愈合的危险因素。

研究设计

回顾性研究。

样本人群

442 只狗(461 处骨折)。

方法

对 2 所教学医院的临床记录和 X 光片进行了回顾。定义了“愈合”、“延迟愈合”、“不愈合”和“畸形愈合”,并描述了骨折、人口统计学、治疗和结局变量。使用 χ 检验和 Mann-Whitney U 检验分别检验“愈合”、“延迟愈合”和“不愈合”之间的比例或中位数差异。使用逻辑回归测试潜在的“延迟或不愈合”解释变量,以确定危险因素。

结果

中位数放射影像学随访时间为 53 天(14-282 天)。13.9%(64/461)的骨折发生延迟愈合,4.6%(21/461)的骨折发生不愈合,0.7%(3/461)的骨折发生畸形愈合。延迟或不愈合的危险因素是年龄(OR 1.21,95%CI 1.12-1.31);粉碎性骨折(OR 4.24,95%CI 2.4-7.5);使用骨移植(所有类型)(OR 3.32,95%CI 1.3-8.5);手术部位感染(OR 3.24,95%CI 1.17-8.97)和主要植入物失败(OR 12.94,95%CI 5.06-33.1)。

结论

年龄较大的狗、粉碎性骨折的狗、手术部位感染或主要植入物失败的狗发生延迟或不愈合的几率增加。玩具品种狗的桡骨和尺骨骨折没有增加发生延迟或不愈合的几率。

临床意义

确定的危险因素应告知骨折计划和预后。玩具品种狗桡骨骨折的预后似乎比以往认为的要好。

相似文献

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Delayed union, non-union and mal-union in 442 dogs.442 例犬的延迟愈合、不愈合和愈合不良。
Vet Surg. 2022 Oct;51(7):1087-1095. doi: 10.1111/vsu.13880. Epub 2022 Aug 27.

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A unified theory of bone healing and nonunion: BHN theory.骨愈合与骨不连的统一理论:BHN理论
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