AndroUrology Centre, Brisbane, Australia.
University of Queensland, Princess Alexandra Hospital, Brisbane, Australia.
Low Urin Tract Symptoms. 2022 Nov;14(6):416-420. doi: 10.1111/luts.12460. Epub 2022 Aug 24.
To evaluate the clinical outcomes and patient satisfaction rate between men aged under and over 70 years who underwent artificial urinary sphincter (AUS) surgery.
A prospective review of all men who received AUS between January 2008 and January 2018 was undertaken with a minimum 24-month review. All patient demographics and surgical outcomes including data on the Incontinence Impact Questionnaire, Patient Global Impression of Improvement (PGI-I) and National Surgical Quality Improvement Program Frailty Index (NSQIP-FI) scores, as well as patient satisfaction rates, were recorded.
Of the 245 AUS implanted, 60 patients were aged ≥70 years with 45 virgin cases and 15 revision AUS. Reduction in mean pad use and weight over 24 hours were significant at 0.21 (0-1) pads and 8 (0-30) g in both groups with no significant difference (P = 0.76). Kaplan-Meier estimates of AUS survival showed no significant difference between men aged ≥ and <70 years at 1 year (98% versus 96%; P = 0.44). The multivariate logistic regression model showed that radiation (adjusted odds ratio [OR] 3.8, 95% CI 1.4-6.8; P < 0.01) was a significant predictor of AUS revision, while age ≥ 70 years (adjusted OR 1.0, 95% CI 0.8-8.8; P = 0.14) and frailty (NSQIP-FI ≥ 0.27 adjusted OR 0.9, 95% CI 0.2-7.6; P = 0.82) were not. There were no significant differences in PGI-I scores (P = 0.43) and overall satisfaction rate (83% versus 84%; P = 0.44) between the two groups.
Men aged ≥70 years reported similar clinical efficacy as men aged <70 years in terms of device survival and satisfaction rates following AUS surgery.
评估年龄在 70 岁以下和 70 岁以上的男性接受人工尿失禁括约肌(AUS)手术的临床结果和患者满意度。
对 2008 年 1 月至 2018 年 1 月期间接受 AUS 手术的所有男性进行前瞻性回顾,随访时间至少为 24 个月。记录所有患者的人口统计学数据和手术结果,包括失禁影响问卷、患者整体改善印象(PGI-I)和国家手术质量改进计划脆弱指数(NSQIP-FI)评分,以及患者满意度。
在植入的 245 个 AUS 中,有 60 名患者年龄≥70 岁,其中 45 名是初治患者,15 名是 AUS 翻修患者。两组患者的平均尿垫使用量和 24 小时体重减轻均有显著差异,分别为 0.21(0-1)个尿垫和 8(0-30)g,差异无统计学意义(P=0.76)。AUS 生存的 Kaplan-Meier 估计显示,年龄≥70 岁和<70 岁的男性在 1 年时的 AUS 存活率无显著差异(98%与 96%;P=0.44)。多变量逻辑回归模型显示,放疗(调整后的优势比[OR]3.8,95%CI 1.4-6.8;P<0.01)是 AUS 翻修的显著预测因素,而年龄≥70 岁(调整后的 OR 1.0,95%CI 0.8-8.8;P=0.14)和虚弱(NSQIP-FI≥0.27 调整后的 OR 0.9,95%CI 0.2-7.6;P=0.82)则不是。两组患者的 PGI-I 评分(P=0.43)和总体满意度(83%与 84%;P=0.44)无显著差异。
在 AUS 手术后,年龄≥70 岁的男性在设备生存率和满意度方面与年龄<70 岁的男性报告了相似的临床疗效。