Department of Neurology, Minamata City Hospital and Medical Center, Minamata, Japan.
Department of Neurology, Graduate School of Medical Sciences, Kumamoto University.
J Stroke Cerebrovasc Dis. 2022 Oct;31(10):106695. doi: 10.1016/j.jstrokecerebrovasdis.2022.106695. Epub 2022 Aug 30.
The modified Rankin Scale (mRS) is widely used as a measure of post-stroke physical disability in clinical stroke trials; however, it is affected by inter-rater discrepancies. A Japanese version of the simplified mRS questionnaire (J-RASQ) has the potential to overcome the inter-rater discrepancies and might be feasible for clinical surveys. We aimed to determine the reliability of J-RASQ in a telephone survey administered by non-medical staff.
We recruited 103 patients (age = 73 ± 11 years; 57% males) with a history of ischemic stroke who visited the outpatient clinic of the department of neurology at our hospital between March and May, 2021. After obtaining informed consent for participation in the study, a stroke neurologist assessed the mRS score during the visit using the Japanese version of mRS. On the same day, a clerk telephoned the patient or his/her family members to administer the J-RASQ. The percentage of agreement between mRS and J-RASQ scores was evaluated using the kappa coefficient and weighted kappa coefficient.
The median time for the telephone survey was 85 s (interquartile range = 70-135 s). The mRS and J-RASQ scores had an agreement of 63.1%, with a kappa statistic of 0.51 (95% confidence interval [CI] = 0.39-0.63). The weighted kappa statistic, which takes into account the extent of disagreement, was 0.81 (95% CI = 0.75-0.88).
J-RASQ is easy to administer and reliable for assessment in telephone-based surveys performed by non-medical staff.
改良 Rankin 量表（mRS）广泛用于临床脑卒中试验中卒中后身体残疾的衡量标准，但它受到评定者间差异的影响。简化版 mRS 问卷的日文版（J-RASQ）具有克服评定者间差异的潜力，并且可能适用于临床调查。我们旨在确定非医务人员进行电话调查时 J-RASQ 的可靠性。
我们招募了 103 名（年龄=73 ± 11 岁；57%为男性）有缺血性卒中病史的患者，他们于 2021 年 3 月至 5 月期间在我们医院神经内科门诊就诊。在获得参与研究的知情同意后，一位卒中神经病学家在就诊期间使用 mRS 日文版评估 mRS 评分。同一天，一名办事员通过电话联系患者或其家属进行 J-RASQ 调查。使用 Kappa 系数和加权 Kappa 系数评估 mRS 和 J-RASQ 评分之间的一致性百分比。
电话调查的中位数时间为 85 秒（四分位距=70-135 秒）。mRS 和 J-RASQ 评分的一致性为 63.1%，Kappa 统计量为 0.51（95%置信区间[CI]为 0.39-0.63）。考虑到分歧程度的加权 Kappa 统计量为 0.81（95%CI 为 0.75-0.88）。
J-RASQ 易于管理，并且由非医务人员进行电话调查时具有可靠性。
