• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脊麻下行剖宫产术产妇全身麻醉转换率及静脉补充需求的发生率:一项回顾性观察研究。

Incidence of conversion to general anaesthesia and need for intravenous supplementation in parturients undergoing caesarean section under spinal anaesthesia: A retrospective observational study.

作者信息

Stav Michael, Matatov Yuri, Hoffmann Dana, Heesen Philip, Gliesche Vincent, Binyamin Yair, Ioscovich Alexander, Eidelman Leonid A, Orbach-Zinger Sharon

机构信息

Department of Anaesthesia, Beilinson Hospital, Petach Tikvah, and Sackler Medical School, Tel Aviv University, Tel Aviv, Israel.

University of Zurich, Zurich, Switzerland.

出版信息

Acta Anaesthesiol Scand. 2023 Jan;67(1):29-35. doi: 10.1111/aas.14146. Epub 2022 Sep 11.

DOI:10.1111/aas.14146
PMID:36056463
Abstract

BACKGROUND

Conversion from spinal anaesthesia to general anaesthesia (GA) was shown to be associated with more complications. It has been postulated that spinal injection of a low dose of local anaesthetic is a risk factor. We aimed to discover the rate of conversion from spinal anaesthesia to GA in women who received at least 10 mg heavy bupivacaine and opioids and assess its risk factors.

METHODS

All women that underwent spinal anaesthesia for caesarean section from 1 January 2017 to 31 December 2020 were included in this analysis. Spinal anaesthesia was performed according to department protocol using heavy bupivacaine 0.5% 10-13 mg, fentanyl 20 μg, and morphine 0.1 mg. We examined rate of conversion from spinal anaesthesia to GA and rate of need for analgesia/sedation.

RESULTS

There were 1.7% of women that required conversion to GA. Bupivacaine dose (OR 0.54 [95% CI 0.38 to 0.75], p < 0.001), surgery time (OR 1.03 [95% CI 1.02 to 1.04], p < 0.001), emergency caesarean section (OR 1.06 [95% CI 1.16 to 3.76], p = 0.015), and postpartum haemorrhage (OR 5.96 [95% CI 1.09 to 25.18], p = 0.025) were independent predictors of need for conversion to GA. Of the women who had CS under spinal anaesthesia, 4.1% of parturients required intraoperative analgesics/sedatives and 9.1% required anxiolysis.

CONCLUSIONS

A small proportion of women required conversion to GA. This conversion occurred especially with emergency caesarean section and when low spinal bupivacaine doses were used.

摘要

背景

脊髓麻醉转换为全身麻醉(GA)与更多并发症相关。据推测,脊髓注射低剂量局部麻醉剂是一个危险因素。我们旨在发现接受至少10毫克重比重布比卡因和阿片类药物的女性中脊髓麻醉转换为GA的发生率,并评估其危险因素。

方法

纳入2017年1月1日至2020年12月31日期间接受剖宫产脊髓麻醉的所有女性。根据科室方案,使用0.5%重比重布比卡因10 - 13毫克、芬太尼20微克和吗啡0.1毫克进行脊髓麻醉。我们检查了脊髓麻醉转换为GA的发生率以及镇痛/镇静需求率。

结果

1.7%的女性需要转换为GA。布比卡因剂量(比值比[OR]0.54[95%置信区间(CI)0.38至0.75],p<0.001)、手术时间(OR 1.03[95%CI 1.02至1.04],p<0.001)、急诊剖宫产(OR 1.06[95%CI 1.16至3.76],p = 0.015)和产后出血(OR 5.96[95%CI 1.09至25.18],p = 0.025)均为转换为GA需求的独立预测因素。在接受脊髓麻醉下剖宫产的女性中,4.1%的产妇需要术中使用镇痛药/镇静剂,9.1%的产妇需要抗焦虑治疗。

结论

一小部分女性需要转换为GA。这种转换尤其发生在急诊剖宫产以及使用低剂量脊髓布比卡因时。

相似文献

1
Incidence of conversion to general anaesthesia and need for intravenous supplementation in parturients undergoing caesarean section under spinal anaesthesia: A retrospective observational study.脊麻下行剖宫产术产妇全身麻醉转换率及静脉补充需求的发生率:一项回顾性观察研究。
Acta Anaesthesiol Scand. 2023 Jan;67(1):29-35. doi: 10.1111/aas.14146. Epub 2022 Sep 11.
2
Use of hyperbaric versus isobaric bupivacaine for spinal anaesthesia for caesarean section.剖宫产腰麻中使用高压布比卡因与等压布比卡因的比较。
Cochrane Database Syst Rev. 2013 May 31(5):CD005143. doi: 10.1002/14651858.CD005143.pub2.
3
Perfusion index derived from a pulse oximeter can predict the incidence of hypotension during spinal anaesthesia for Caesarean delivery.脉搏血氧仪衍生的灌注指数可预测剖宫产脊髓麻醉期间低血压的发生率。
Br J Anaesth. 2013 Aug;111(2):235-41. doi: 10.1093/bja/aet058. Epub 2013 Mar 21.
4
Duration of motor block with intrathecal ropivacaine versus bupivacaine for caesarean section: a meta-analysis.剖宫产术中鞘内注射罗哌卡因与布比卡因运动阻滞持续时间的Meta分析
Int J Obstet Anesth. 2016 Aug;27:9-16. doi: 10.1016/j.ijoa.2016.03.004. Epub 2016 Mar 17.
5
An observational prospective cohort study of incidence and characteristics of failed spinal anaesthesia for caesarean section.一项关于剖宫产脊髓麻醉失败发生率及特征的前瞻性观察队列研究。
Int J Obstet Anesth. 2009 Jul;18(3):237-41. doi: 10.1016/j.ijoa.2009.01.010. Epub 2009 May 17.
6
Height-based dosing algorithm of bupivacaine in spinal anaesthesia for decreasing maternal hypotension in caesarean section without prophylactic fluid preloading and vasopressors: study protocol for a randomised controlled non-inferiority trial.基于身高的布比卡因椎管内麻醉剂量算法在剖宫产中减少产妇低血压:一项无预防性液体预充和血管加压素的随机对照非劣效性试验研究方案。
BMJ Open. 2019 May 16;9(5):e024912. doi: 10.1136/bmjopen-2018-024912.
7
A randomised controlled trial of the effect of a head-elevation pillow on intrathecal local anaesthetic spread in caesarean section.一项关于头高位枕对剖宫产术中鞘内局部麻醉药扩散影响的随机对照试验。
Int J Obstet Anesth. 2015 Nov;24(4):303-7. doi: 10.1016/j.ijoa.2015.08.004. Epub 2015 Aug 11.
8
Effectiveness of Hydromorphone Hydrochloride Combined with Bupivacaine for Combined Spinal and Epidural Anaesthesia in Reducing Postpartum Urinary Retention: A Retrospective Study.氢吗啡酮盐酸盐联合布比卡因用于蛛网膜下腔-硬膜外联合麻醉对减少产后尿潴留的效果:一项回顾性研究。
Arch Esp Urol. 2024 Jun;77(5):570-576. doi: 10.56434/j.arch.esp.urol.20247705.77.
9
Hyperbaric prilocaine vs. hyperbaric bupivacaine for spinal anaesthesia in women undergoing elective caesarean section: a comparative randomised double-blind study.高压布比卡因与高压丙胺卡因用于择期剖宫产术女性脊髓麻醉的比较:一项随机双盲对照研究
Anaesthesia. 2021 Jun;76(6):777-784. doi: 10.1111/anae.15342. Epub 2021 Jan 11.
10
Subarachnoid anaesthesia in caesarean delivery: effects on alertness.剖宫产术中蛛网膜下腔麻醉:对警觉性的影响。
Minerva Anestesiol. 2003 Nov;69(11):809-19, 819-24.

引用本文的文献

1
Prevention and management of intraoperative pain during Caesarean section.剖宫产术中疼痛的预防与管理
BJA Educ. 2025 Feb;25(2):50-56. doi: 10.1016/j.bjae.2024.09.006. Epub 2024 Nov 22.
2
Failed spinal anesthesia for cesarean delivery: prevention, identification and management.剖宫产脊髓麻醉失败:预防、识别与处理
Curr Opin Anaesthesiol. 2024 Jun 1;37(3):207-212. doi: 10.1097/ACO.0000000000001362. Epub 2024 Feb 15.