New York City Mayor's Office of Management and Budget, New York, NY, USA.
New York City Mayor's Office of Management and Budget, New York, NY, USA.
Lancet Public Health. 2022 Sep;7(9):e754-e762. doi: 10.1016/S2468-2667(22)00196-7.
COVID-19 vaccines have been available to all adults in the USA since April, 2021, but many adults remain unvaccinated. We aimed to assess the joint effect of a proof-of-vaccination requirement, incentive payments, and employer-based mandates on rates of adult vaccination in New York City (NYC).
We constructed a synthetic control group for NYC composed of other counties in the core of large, metropolitan areas in the USA. The vaccination outcomes for NYC were compared against those of the synthetic control group from July 26, 2021, to Nov 1, 2021, to determine the differential effects of the policies. Analyses were conducted on county-level vaccination data reported by the Centers for Disease Control and Prevention. The synthetic control group was constructed by matching on county-level preintervention vaccination outcomes, partisanship, economic attributes, demographics, and metropolitan area population. Statistical inference was conducted using placebo tests for non-treated counties.
The synthetic control group resembled NYC across attributes used in the matching process. The cumulative adult vaccination rate for NYC (in adults aged 18 years or older who received at least one dose of an authorised COVID-19 vaccine) increased from 72·5% to 89·4% (+16·9 percentage points [pp]) during the intervention period, compared with an increase from 72·5% to 83·2% (+10·7 pp) for the synthetic control group, a difference of 6·2 pp (95% CI 1·4-10·7), or 410 201 people (90 966-706 532). Daily vaccinations for NYC were consistently higher than those in the synthetic control group, a pattern that started shortly after the start of the intervention period.
The combination of a proof-of-vaccination requirement, incentive payments, and vaccine mandates increased vaccination rates among adults in NYC compared with jurisdictions that did not use the same measures. Whether the impact of these measures occurred by inducing more people to get vaccinated, or by accelerating vaccinations that would have occurred later, the increase in vaccination rates likely averted illness and death.
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自 2021 年 4 月以来,美国所有成年人都可以接种 COVID-19 疫苗,但仍有许多成年人未接种疫苗。我们旨在评估疫苗接种证明要求、奖励金和雇主强制接种政策对纽约市(NYC)成年人疫苗接种率的联合影响。
我们为 NYC 构建了一个由美国大型都会区核心的其他县组成的合成对照组。从 2021 年 7 月 26 日到 11 月 1 日,将 NYC 的疫苗接种结果与合成对照组进行比较,以确定政策的差异影响。分析使用疾病控制与预防中心报告的县级疫苗接种数据进行。通过匹配县一级接种前的疫苗接种结果、党派、经济属性、人口统计数据和都会区人口,构建了合成对照组。使用对未处理县的安慰剂检验进行统计推断。
合成对照组在匹配过程中使用的属性与 NYC 相似。NYC 的成年接种率(18 岁或以上至少接种一剂授权 COVID-19 疫苗的成年人)在干预期间从 72.5%增加到 89.4%(增加 16.9 个百分点[pp]),而合成对照组从 72.5%增加到 83.2%(增加 10.7 个百分点),差异为 6.2 个百分点(95%CI 1.4-10.7),或 410201 人(90966-706532)。NYC 的每日疫苗接种量始终高于合成对照组,这种模式在干预开始后不久就出现了。
疫苗接种证明要求、奖励金和疫苗接种强制令的结合,使 NYC 的成年人疫苗接种率高于未使用相同措施的司法管辖区。这些措施的影响是否通过促使更多人接种疫苗,或通过加速以后会发生的疫苗接种来实现,疫苗接种率的提高都可能避免了疾病和死亡。
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