Gonçalo Moniz Research Centre, Oswaldo Cruz Foundation, Salvador, Brazil.
Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Transbound Emerg Dis. 2022 Nov;69(6):3153-3159. doi: 10.1111/tbed.14692. Epub 2022 Sep 12.
Schistosomiasis is a tropical neglected disease commonly associated with rural areas; however, urban schistosomiasis has been reported worldwide, and increasing urbanization is one of the most important demographic shifts of the 20th and now 21st centuries. The pattern of urbanization is not uniform so that within the same city the rates and sources of population increase vary. Here, we report on the parasite composition in one neighbourhood in the metropolitan area of Salvador, Bahia, Brazil. Using epidemiological data and population genetics, we find evidence for local transmission and maintenance of Schistosoma mansoni infection within an urban population and little contribution from rural-urban migration. Our findings provide direction for local mitigation strategies and to assist the public living in this neighbourhood to interrupt the local transmission cycle.
血吸虫病是一种热带被忽视的疾病，通常与农村地区有关；然而，世界各地都有城市血吸虫病的报告，而城市化的不断增加是 20 世纪和现在 21 世纪最重要的人口结构变化之一。城市化的模式并不统一，因此在同一个城市中，人口增长的速度和来源也有所不同。在这里，我们报告了巴西巴伊亚州萨尔瓦多大都市区的一个街区的寄生虫组成。利用流行病学数据和人口遗传学，我们发现有证据表明，在城市人口中存在曼氏血吸虫感染的本地传播和维持，而农村向城市的迁移贡献很小。我们的研究结果为当地的缓解策略提供了方向，并帮助居住在这个街区的公众中断本地传播周期。
