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创伤患者的区域麻醉:一项质量改进研究。

Regional anesthesia in trauma patients: a quality improvement study.

机构信息

Division of Trauma Anesthesia, Cedars-Sinai Medical Center, 8700 Beverly Blvd., North Tower, Suite 8211, Los Angeles, CA, 90048, USA.

Cedars-Sinai Medical Center, 8700 Beverly Blvd., North Tower, Suite 8211, Los Angeles, CA, 90048, USA.

出版信息

Eur J Trauma Emerg Surg. 2023 Feb;49(1):495-504. doi: 10.1007/s00068-022-02097-5. Epub 2022 Sep 4.

Abstract

BACKGROUND

Traumatic injury is associated with severe pain that is often inadequately managed. Opioids remain the mainstay of pain management in this population because of their ease of use. However, opioids have significant side effects including nausea, delirium, and respiratory depression. Regional anesthesia has been demonstrated in the perioperative setting to provide superior analgesia with fewer side effects and a reduced length of stay. Similarly, regional anesthesia has been shown to improve morbidity for extremity fractures and dislocations when introduced early.

METHODS

This was a prospective cohort quality improvement study evaluating the use of earlier and more consistent regional anesthesia procedures in 28 consecutive trauma patients at a large Canadian trauma center. In this quasi-experimental before and after study, we identified all trauma patients with an ISS < 15 that would have been candidates for a peripheral nerve block and compared them to the study population that received a regional anesthesia nerve block within 24 h of admission.

RESULTS

The introduction of a multidisciplinary pain program into our level 1 regional trauma center resulted in a decrease in pain severity and opioid consumption of 55% and 61%, respectively, after 24 h of admission. Length of stay in the emergency department decreased (11.5 ± 6.9 vs. 4.9 ± 4.4 h; p < 0.01) while hospital length of stay did not (338 ± 276 vs. 285 ± 205 h; p = 0.4).

CONCLUSION

This quality improvement proof-of-principle study reveals the potential advantages for regional anesthesia, such as decreased emergency department use, opioid consumption, and pain severity. Further randomized trials are necessary, however, to describe a direct benefit from peripheral nerve blockade on reducing length of stay for trauma patients.

摘要

背景

创伤与严重疼痛有关,而这种疼痛往往得不到充分的治疗。由于其使用方便,阿片类药物仍然是该人群疼痛管理的主要药物。然而,阿片类药物有显著的副作用,包括恶心、神志不清和呼吸抑制。区域麻醉在围手术期已被证明能提供更好的镇痛效果,副作用更少,住院时间更短。同样,早期引入区域麻醉也被证明能改善四肢骨折和脱位患者的发病率。

方法

这是一项前瞻性队列质量改进研究,评估了在加拿大一家大型创伤中心的 28 例连续创伤患者中更早和更一致地使用区域麻醉程序。在这项准实验性的前后研究中,我们确定了所有 ISS<15 的创伤患者,这些患者都有可能接受外周神经阻滞,并将他们与在入院后 24 小时内接受区域麻醉神经阻滞的研究人群进行比较。

结果

将多学科疼痛方案引入我们的 1 级区域创伤中心,导致入院后 24 小时内疼痛严重程度和阿片类药物的消耗分别降低了 55%和 61%。急诊停留时间缩短(11.5±6.9 与 4.9±4.4 小时;p<0.01),而住院停留时间没有缩短(338±276 与 285±205 小时;p=0.4)。

结论

这项质量改进初步研究揭示了区域麻醉的潜在优势,如减少急诊使用、阿片类药物的消耗和疼痛严重程度。然而,还需要进一步的随机试验来描述外周神经阻滞对减少创伤患者住院时间的直接益处。

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