Turner Alyssa L, Stevenson Michelle D, Cross Keith P
From the Division of Emergency Medicine, Department of Pediatrics, Kosair Children's Hospital, University of Louisville, Louisville, KY.
Pediatr Emerg Care. 2014 Apr;30(4):227-9. doi: 10.1097/PEC.0000000000000101.
The objective of this study was to compare the duration of analgesia, need for analgesic medications, and pain-related nursing interventions in patients who did and did not receive ultrasound-guided femoral nerve blocks for femur fracture pain.
This is a retrospective, preimplementation and postimplementation cohort study. An emergency department log of patients receiving femoral nerve blocks for femur fracture pain was compared with a similar cohort of patients with femur fractures who did not receive nerve blocks. The primary outcome is time from initial pain treatment until the next dose of analgesic. Data were analyzed using Kaplan-Meier methods. Secondary outcomes include number of doses of pain medication, total amount of morphine given, and number of pain-related nursing interventions. Data were analyzed with the Mann-Whitney U test.
Eighty-one patients met inclusion/exclusion criteria: 50 in the preimplementation cohort and 31 in the postimplementation group. The median times until next dose of analgesic medication were 2.2 hours (interquartile range [IQR], 1.2-3.4 hours) in the preimplementation group and 6.1 hours (IQR, 3.8-9.5 hours) in the postimplementation group (P < 0.001). The median numbers of doses of pain medication were 0.3 per hour (IQR, 0.25-0.5 per hour) in the preimplementation group and 0.15 per hour (IQR, 0.07-0.3 per hour) in the postimplementation group. The median total doses of morphine were 14.8 µg/kg per hour (IQR, 9.4-19.2 µg/kg per hour) in the preimplementation group and 6.5 µg/kg per hour (IQR, 0-12.2 µg/kg per hour) in the postimplementation group (P = 0.01). The median numbers of nursing interventions were 0.4 per hour (IQR, 0.25-0.5 per hour) in the preimplementation group and 0.15 per hour (IQR, 0.1-0.2 per hour) in the postimplementation group (P < 0.001).
Patients who received ultrasound-guided femoral nerve block for femur fracture pain had longer duration of analgesia, required fewer doses of analgesic medications, and needed fewer nursing interventions than those receiving systemic analgesic medication alone.
本研究的目的是比较接受和未接受超声引导下股神经阻滞治疗股骨骨折疼痛的患者的镇痛持续时间、镇痛药物需求以及与疼痛相关的护理干预情况。
这是一项回顾性的实施前和实施后队列研究。将因股骨骨折疼痛接受股神经阻滞的患者的急诊科记录与未接受神经阻滞的类似股骨骨折患者队列进行比较。主要结局是从初始疼痛治疗到下一次镇痛药物剂量的时间。使用Kaplan-Meier方法分析数据。次要结局包括镇痛药物剂量、给予的吗啡总量以及与疼痛相关的护理干预次数。使用Mann-Whitney U检验分析数据。
81名患者符合纳入/排除标准:实施前队列中有50名,实施后组中有31名。实施前组直到下一次镇痛药物剂量的中位时间为2.2小时(四分位间距[IQR],1.2 - 3.4小时),实施后组为6.1小时(IQR,3.8 - 9.5小时)(P < 0.001)。实施前组镇痛药物剂量的中位数为每小时0.3剂(IQR,每小时0.25 - 0.5剂),实施后组为每小时0.15剂(IQR,每小时0.07 - 0.3剂)。实施前组吗啡的中位总剂量为每小时14.8μg/kg(IQR,9.4 - 19.2μg/kg),实施后组为每小时6.5μg/kg(IQR,0 - 12.2μg/kg)(P = 0.01)。实施前组护理干预的中位数为每小时0.4次(IQR,每小时0.25 - 0.5次),实施后组为每小时0.15次(IQR,每小时0.1 - 0.2次)(P < 0.001)。
与仅接受全身镇痛药物治疗的患者相比,接受超声引导下股神经阻滞治疗股骨骨折疼痛的患者镇痛持续时间更长,所需镇痛药物剂量更少,护理干预需求也更少。