Medicine & Rheumatology Unit, IRCCS Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy.
Diagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy.
Radiol Med. 2022 Oct;127(10):1159-1169. doi: 10.1007/s11547-022-01545-x. Epub 2022 Sep 4.
Diffuse idiopathic skeletal hyperostosis (DISH) is a benign condition characterized by ossification of the spine and prominent enthesopathies. Highly heterogeneous epidemiological figures have been reported in the literature, while in Italy the largest study has been conducted in 1992. The aim of our research is to contribute updated information about prevalence of DISH in Italy and to describe the clinical and radiographic characteristics associated with the disorder.
A retrospective review of lumbosacral spine, thoracic spine and pelvis radiographs was performed. Consecutive patients visiting the emergency department of our Institution over 3 years were enrolled. Presence of DISH was evaluated applying the Resnick and Niwayama criteria. Clinical and radiological features were also assessed.
We included 1012 individuals (60.6% women), and DISH was present in 130 cases. The overall prevalence of DISH was 12.8% (95% CI 10.8-15.1), with higher figures in the male sample (16.8%) than in females (10.3%). In binary logistic regression adjusted for age, BMI (OR 1.50, p < 0.001) diabetes (OR 1.85, p = 0.003), hypertension (OR 2.04, p = 0.007) ischiopubic enthesopathy (OR 7.08, p < 0.001), iliac crest enthesopathy (OR 4.63, p < 0.001) and greater trochanter enthesopathy (OR 3.51, p < 0.001), were significantly associated with the condition.
The prevalence of DISH observed in our study is consistent with previous literature, and we confirm that the disorder is more frequently retrieved in men and that it is associated with the presence of metabolic disorders and pelvic enthesopathy. Knowledge about the epidemiology and characteristics of DISH is needed to properly identify the condition.
弥漫特发性骨肥厚（DISH）是一种良性疾病，其特征为脊柱骨化和明显的肌腱病。文献中报道了高度异质的流行病学数据，而在意大利，最大的研究是在 1992 年进行的。我们的研究旨在提供有关 DISH 在意大利的患病率的最新信息，并描述与该疾病相关的临床和放射学特征。
回顾性分析了腰骶部、胸段和骨盆的 X 线片。连续 3 年来我院急诊科就诊的患者均纳入研究。应用 Resnick 和 Niwayama 标准评估 DISH 的存在。还评估了临床和放射学特征。
我们纳入了 1012 名个体（60.6%为女性），其中 130 例存在 DISH。DISH 的总体患病率为 12.8%（95%CI 10.8-15.1），男性样本（16.8%）高于女性（10.3%）。在调整年龄、BMI（OR 1.50，p<0.001）、糖尿病（OR 1.85，p=0.003）、高血压（OR 2.04，p=0.007）、坐骨耻骨肌腱病（OR 7.08，p<0.001）、髂嵴肌腱病（OR 4.63，p<0.001）和大转子肌腱病（OR 3.51，p<0.001）的二元逻辑回归中，这些因素与该疾病显著相关。
我们的研究中观察到的 DISH 患病率与先前的文献一致，我们确认该疾病在男性中更常见，并且与代谢紊乱和骨盆肌腱病有关。了解 DISH 的流行病学和特征有助于正确识别该疾病。
