Department of Biomedical Engineering, School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China.
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Comput Methods Programs Biomed. 2022 Oct;225:107089. doi: 10.1016/j.cmpb.2022.107089. Epub 2022 Aug 28.
Cardiotocography, commonly called CTG, has become an indispensable auxiliary examination in obstetrics. Generally, CTG is provided in the form of a report, so the fetal heart rate and uterine contraction signals have to be extracted from the CTG images. However, most studies focused on reading data for a single curve, and the influence of complex backgrounds was usually not considered.
An efficient signal extraction method was proposed for the binary CTG images with complex backgrounds. Firstly, the images' background grids and symbol noise were removed by templates. Then a morphological method was used to fill breakpoints of curves. Moreover, the projection map was utilized to localize the area and the starting and ending positions of curves. Subsequently, data of the curves were extracted by column scanning. Finally, the amplitude of the extracted signal was calibrated.
This study had tested 552 CTG images simulated using the CTU-UHB database. The correlation coefficient between the extracted and original signals was 0.9991 ± 0.0030 for fetal heart rate and 0.9904 ± 0.0208 for uterine contraction, and the mean absolute error of fetal heart rate and uterine contraction were 2.4658 ± 1.8446 and 1.8025 ± 0.6155, and the root mean square error of fetal heart rate and uterine contraction were 4.2930 ± 2.9771 and 2.5214 ± 0.9640, respectively. After being validated using 293 clinical authentic CTG images, the extracted signals were remarkably similar to the original counterparts, and no significant differences were observed.
The proposed method could effectively extract the fetal heart rate and uterine contraction signals from the binary CTG images with complex backgrounds.
胎心监护图(cardiotocography,简称 CTG)已成为产科不可或缺的辅助检查手段。通常,CTG 以报告的形式呈现,因此必须从 CTG 图像中提取胎儿心率和子宫收缩信号。然而,大多数研究都集中在读取单一曲线的数据上,通常不考虑复杂背景的影响。
提出了一种用于具有复杂背景的二进制 CTG 图像的高效信号提取方法。首先,使用模板去除图像的背景网格和符号噪声。然后,使用形态学方法填充曲线的断点。此外,使用投影图定位曲线的区域和起始及结束位置。接着,通过列扫描提取曲线的数据。最后,对提取信号的幅度进行校准。
本研究使用 CTU-UHB 数据库模拟了 552 张 CTG 图像。提取信号与原始信号的相关系数在胎儿心率和子宫收缩方面分别为 0.9991±0.0030 和 0.9904±0.0208,胎儿心率和子宫收缩的平均绝对误差分别为 2.4658±1.8446 和 1.8025±0.6155,胎儿心率和子宫收缩的均方根误差分别为 4.2930±2.9771 和 2.5214±0.9640。使用 293 份临床真实 CTG 图像进行验证后,提取的信号与原始信号非常相似,没有显著差异。
该方法可以有效地从具有复杂背景的二进制 CTG 图像中提取胎儿心率和子宫收缩信号。