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[肠道黏液屏障与烧伤后肠道损伤修复的研究进展]

[Research progress of intestinal mucus barrier and the repair of intestinal damage after burn injury].

作者信息

Wu D, Su S, Wei Y, Peng X

机构信息

Clinical Medical Research Center, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.

Clinical Medical Research Center, Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Aug 20;38(8):788-793. doi: 10.3760/cma.j.cn501225-20220701-00280.

Abstract

The intestinal mucus layer is the first line of innate host defense and provides energy for the growth of the intestinal flora. In addition, it plays an important role in regulating intestinal microecology and maintaining intestinal homeostasis. This paper reviews the synthesis, secretion, processing, and modification of intestinal mucus, and focuses on the effect of intestinal mucus barrier on intestinal injury repair and the regulation of intestinal mucus barrier by special nutrients after burn injury.

摘要

肠道黏液层是宿主先天性防御的第一道防线,为肠道菌群的生长提供能量。此外,它在调节肠道微生态和维持肠道稳态方面发挥着重要作用。本文综述了肠道黏液的合成、分泌、加工和修饰,并重点探讨了肠道黏液屏障对烧伤后肠道损伤修复的影响以及特殊营养物质对烧伤后肠道黏液屏障的调节作用。

相似文献

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[Research progress of intestinal mucus barrier and the repair of intestinal damage after burn injury].[肠道黏液屏障与烧伤后肠道损伤修复的研究进展]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Aug 20;38(8):788-793. doi: 10.3760/cma.j.cn501225-20220701-00280.
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Development and Functional Properties of Intestinal Mucus Layer in Poultry.家禽肠道黏膜层的发育和功能特性。
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本文引用的文献

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Mucus sialylation determines intestinal host-commensal homeostasis.黏蛋白唾液酸化决定肠道共生稳态。
Cell. 2022 Mar 31;185(7):1172-1188.e28. doi: 10.1016/j.cell.2022.02.013. Epub 2022 Mar 17.

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