Boyano M T, Martín Esteban M, Díaz Pena J M, Ojeda J A
An Esp Pediatr. 1987 Apr;26(4):235-40.
Two hundred and thirty children with suspected food allergy have been reviewed retrospectively. One hundred and nine fulfilled the following three selection criteria: suggestive anamnesis, presence of specific IgE antibodies (in serum or by skin prick test), and having been reassessed at least once. The major clinical data analyzed were: age of onset, sensitising foods, symptomatology and diagnostic procedures. The results show a mean age of onset for food allergy of 11.5 months, with variations related to the sensitizing food, cow's milk allergy being the earliest in onset time. The most frequent sensitizing foods in this group of patients were eggs, fish and cow's milk. The skin and the gastrointestinal tract have been the most affected shock organs, both together or isolated; respiratory symptoms were an uncommon finding and their isolated presentation as the sole manifestation of food allergy exceptional. The skin prick tests were positive in 99.2 percent of the sensitizations and in 84 percent high levels of specific IgE antibodies were found. Food allergy seems to be a common situation in children, clinical symptomatology is similar to that of the other atopic diseases and the diagnosis is based on the demonstration of specific IgE antibodies against the sensitizing foods.
对230名疑似食物过敏的儿童进行了回顾性研究。109名儿童符合以下三项入选标准:有提示性的既往史、存在特异性IgE抗体(血清中或通过皮肤点刺试验)以及至少接受过一次重新评估。分析的主要临床数据包括:发病年龄、致敏食物、症状表现和诊断程序。结果显示,食物过敏的平均发病年龄为11.5个月,发病时间因致敏食物而异,牛奶过敏发病最早。该组患者中最常见的致敏食物是鸡蛋、鱼类和牛奶。皮肤和胃肠道是受影响最严重的靶器官,可同时或单独受累;呼吸道症状并不常见,单独出现作为食物过敏的唯一表现则更为罕见。99.2%的致敏患者皮肤点刺试验呈阳性,84%的患者发现特异性IgE抗体水平较高。食物过敏在儿童中似乎很常见,临床症状与其他特应性疾病相似,诊断基于针对致敏食物的特异性IgE抗体的检测。