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骨盆骨折手术治疗相关并发症的发生率及危险因素。

Rates and risk factors of complications associated with operative treatment of pelvic fractures.

机构信息

Department of Trauma Surgery, Leiden University Medical Centre, Leiden, The Netherlands.

Department of Trauma Surgery, Haaglanden Medical Centre, The Hague, The Netherlands.

出版信息

Eur J Orthop Surg Traumatol. 2023 Jul;33(5):1973-1980. doi: 10.1007/s00590-022-03375-z. Epub 2022 Sep 4.

Abstract

PURPOSE

Post-operative complications following fixation of pelvic fractures can lead to mortality and increased morbidity. Available literature regarding complications is heterogeneous and knowledge on risk factors is limited. This study aims to identify the most common post-operative complications and their possible risk factors following pelvic fracture surgery.

METHODS

A retrospective cohort study was performed in two level-1 trauma centers in the Netherlands between January 2015 and January 2021. Included patients were all adult patients (≥ 18 years) with an operatively treated pelvic fracture (pelvic ring and/or acetabular fractures). Post-operative complications included surgical site infections (SSI), material-related complications, neurological complications, malunion/non-union and performed reoperations. A forward stepwise multivariable logistic regression analysis was used to identify any risk factors associated with these complications.

RESULTS

Complications occurred in 55 (24%) of the 233 included patients. SSI's were most common, occurring in 34 (15%) patients. Duration of surgery (odds ratio 1.01 per minute, 95% confidence interval 1.00-1.01) and obesity (odds ratio 1.10 per BMI point, 95% confidence interval 1.29-7.52) were independent risk factors for development of SSI. Less common post-operative complications were material-related complications (8%) and neurological damage (5%).

CONCLUSION

Limiting operation time by using less invasive and less time-consuming surgical approaches may reduce the risk of SSI. More awareness and post-operative screening for early signs of SSI is mandatory, especially in obese patients. Future research should include large prospective patient cohorts to determine risk factors for other post-operative complications associated with pelvic fracture surgery.

摘要

目的

骨盆骨折固定术后的并发症可导致死亡率增加和发病率上升。关于并发症的现有文献存在异质性,对危险因素的了解有限。本研究旨在确定骨盆骨折手术后最常见的术后并发症及其可能的危险因素。

方法

本研究是在荷兰的两家一级创伤中心进行的回顾性队列研究。纳入的患者均为接受手术治疗的骨盆骨折(骨盆环和/或髋臼骨折)的成年患者(≥18 岁)。术后并发症包括手术部位感染(SSI)、材料相关并发症、神经并发症、愈合不良/不愈合和再次手术。采用逐步向前多变量逻辑回归分析来确定与这些并发症相关的任何危险因素。

结果

233 例纳入患者中,55 例(24%)发生并发症。SSI 最常见,有 34 例(15%)患者发生。手术时间(每增加 1 分钟,比值比为 1.01,95%置信区间为 1.00-1.01)和肥胖(每 BMI 增加 1 个点,比值比为 1.10,95%置信区间为 1.29-7.52)是 SSI 发展的独立危险因素。较常见的术后并发症包括材料相关并发症(8%)和神经损伤(5%)。

结论

通过使用微创和耗时更少的手术方法来限制手术时间,可能会降低 SSI 的风险。需要更多的认识和术后筛查,以早期发现 SSI 的迹象,特别是在肥胖患者中。未来的研究应包括大型前瞻性患者队列,以确定与骨盆骨折手术相关的其他术后并发症的危险因素。

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本文引用的文献

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The effect of body mass index on the risk of surgical site infection.体重指数对手术部位感染风险的影响。
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Factors affecting mortality and reoperations in high-energy pelvic fractures.影响高能骨盆骨折死亡率及再次手术的因素
Eur J Orthop Surg Traumatol. 2018 Oct;28(7):1273-1282. doi: 10.1007/s00590-018-2203-1. Epub 2018 Apr 19.

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