Bijan Sara, Filutowski Oliver R, Safari Sara
Ophthalmology, University of South Florida, Tampa, USA.
Medicine, University of South Florida (USF) Health Morsani College of Medicine, Tampa, USA.
Cureus. 2022 Aug 1;14(8):e27569. doi: 10.7759/cureus.27569. eCollection 2022 Aug.
While vitamin A deficiency is a leading cause of blindness globally, it is uncommon in the developed world. Here we describe the unique presentation of a young man in the United States with keratomalacia from vitamin A deficiency related to pancreatic insufficiency. The patient presented with bilateral blurry vision that persisted for two weeks, significant unintentional weight loss, orthostatic hypotension, and profuse diarrhea. Upon slit-lamp examination, bilateral corneal opacities were appreciated. After completing additional testing, it became clear that the patient's corneal opacities were related to vitamin A deficiency from pancreatic insufficiency.
虽然维生素A缺乏是全球失明的主要原因,但在发达国家并不常见。在此,我们描述了一名美国年轻人因胰腺功能不全导致维生素A缺乏而出现角膜软化症的独特病例。该患者出现双侧视力模糊,持续两周,伴有明显的非故意体重减轻、直立性低血压和大量腹泻。裂隙灯检查发现双侧角膜混浊。经过进一步检查,明确患者的角膜混浊与胰腺功能不全导致的维生素A缺乏有关。