Zamora Edgar, Rivera Valladares Louisiana, Edema Ukuemi, Freeman Leonard M
Division of Nuclear Medicine, Department of Radiology, Montefiore Medical Center and the Albert Einstein College of Medicine, The Bronx, New York, United States.
Department of Pathology, Montefiore Medical Center and the Albert Einstein College of Medicine, The Bronx, New York, United States.
World J Nucl Med. 2022 Aug 16;21(3):244-247. doi: 10.1055/s-0042-1750439. eCollection 2022 Sep.
Hepatocellular carcinoma (HCC) is the most common type of liver cancer, with a poor median survival when left untreated. Extrahepatic metastases involving musculoskeletal tissues typically present with concomitant nonosseous metastases at the time of diagnosis. A 61-year-old male on 1-year remission, following transarterial chemoembolization of a 2.3-cm hepatic HCC 1 year before, presented with a 2-month history of left wrist pain and swelling after falling on an outstretched hand. Computed tomographic scan revealed diffuse osteolytic lesions localized in left hand and distal forearm, associated with equivocal diffuse activity on bone scan. Subsequent surgical debridement revealed metastatic hepatocellular carcinoma.
肝细胞癌（HCC）是最常见的肝癌类型，若不治疗，中位生存期较短。涉及肌肉骨骼组织的肝外转移在诊断时通常伴有非骨转移。一名61岁男性，1年前对2.3厘米的肝HCC进行了经动脉化疗栓塞，目前处于缓解期1年，在伸手跌倒后出现了2个月的左手腕疼痛和肿胀病史。计算机断层扫描显示左手和前臂远端有弥漫性溶骨性病变，骨扫描显示有可疑的弥漫性活性。随后的手术清创显示为转移性肝细胞癌。
