Varkaneh Zahra Kord, Karampourian Arezou, Oshvandi Khodayar, Basiri Zahra, Mohammadi Younes
Department of Medical Surgical Nursing, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.
Urology and Nephrology Research Center, Chronic Diseases (Home Care) Research Center, Department of Medical Surgical Nursing, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.
Contemp Clin Trials Commun. 2022 Aug 21;29:100976. doi: 10.1016/j.conctc.2022.100976. eCollection 2022 Oct.
Pain is one of the most significant symptoms of rheumatoid arthritis that reduce the quality of life. The purpose of the study was to determine the effect of eucalyptus on pain and the quality of life in patients with rheumatoid arthritis.
In this randomized clinical trial, 70 patients with rheumatoid arthritis were selected by random sampling. In the eucalyptus group, 1 mL of eucalyptus oil was inhaled for 5 min, 3 times a day, for one month. The control group received placebo inhalation. Both groups used routine treatments. Data were collected using a questionnaire of demographics, the numerical pain rating scale (NRS), and Quality of Life (SF-12). Statistical analysis was done using 19th edition SPSS software and applied on paired -test, chi-square, Fisher's exact test, and analysis of covariance.
The mean score of pain severity in the eucalyptus group significantly decreased in comparison with the control group (P < 0.001). The severity of pain there was no statistical difference in both groups before, the first, and the second weeks after the intervention, (p > 0.05); however, in the third and fourth weeks after the intervention, the mean severity of pain in the eucalyptus group was lower than in the control group, and these differences were statistically significant between the two groups (p < 0.05). Also, the patients' quality of life in the eucalyptus group was increased significantly (P < 0.001).
The eucalyptus leads to pain reduction, and consequently, improves the quality of life of patients with rheumatoid arthritis.
IRCT20160110025929N15 Registration date: ; https://en.irct.ir/trial/33573.
疼痛是类风湿性关节炎最显著的症状之一,会降低生活质量。本研究的目的是确定桉叶油对类风湿性关节炎患者疼痛及生活质量的影响。
在这项随机临床试验中,通过随机抽样选取了70例类风湿性关节炎患者。桉叶油组患者每天吸入1毫升桉叶油,每次5分钟,共3次,持续1个月。对照组接受安慰剂吸入。两组均采用常规治疗。使用人口统计学问卷、数字疼痛评分量表(NRS)和生活质量量表(SF - 12)收集数据。使用第19版SPSS软件进行统计分析,并应用配对检验、卡方检验、Fisher精确检验和协方差分析。
与对照组相比,桉叶油组的疼痛严重程度平均得分显著降低(P < 0.001)。干预前、干预后第一周和第二周,两组的疼痛严重程度无统计学差异(p > 0.05);然而,在干预后的第三周和第四周,桉叶油组的疼痛平均严重程度低于对照组,两组之间的这些差异具有统计学意义(p < 0.05)。此外,桉叶油组患者的生活质量显著提高(P < 0.001)。
桉叶油可减轻疼痛,从而改善类风湿性关节炎患者的生活质量。
IRCT20160110025929N15 注册日期:;https://en.irct.ir/trial/33573 。