Suppr超能文献

桉叶油吸入对类风湿性关节炎疼痛及生活质量的影响。

The effect of eucalyptus inhalation on pain and the quality of life in rheumatoid arthritis.

作者信息

Varkaneh Zahra Kord, Karampourian Arezou, Oshvandi Khodayar, Basiri Zahra, Mohammadi Younes

机构信息

Department of Medical Surgical Nursing, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.

Urology and Nephrology Research Center, Chronic Diseases (Home Care) Research Center, Department of Medical Surgical Nursing, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.

出版信息

Contemp Clin Trials Commun. 2022 Aug 21;29:100976. doi: 10.1016/j.conctc.2022.100976. eCollection 2022 Oct.

Abstract

PROBLEM CONSIDERED

Pain is one of the most significant symptoms of rheumatoid arthritis that reduce the quality of life. The purpose of the study was to determine the effect of eucalyptus on pain and the quality of life in patients with rheumatoid arthritis.

METHODS

In this randomized clinical trial, 70 patients with rheumatoid arthritis were selected by random sampling. In the eucalyptus group, 1 mL of eucalyptus oil was inhaled for 5 min, 3 times a day, for one month. The control group received placebo inhalation. Both groups used routine treatments. Data were collected using a questionnaire of demographics, the numerical pain rating scale (NRS), and Quality of Life (SF-12). Statistical analysis was done using 19th edition SPSS software and applied on paired -test, chi-square, Fisher's exact test, and analysis of covariance.

RESULTS

The mean score of pain severity in the eucalyptus group significantly decreased in comparison with the control group (P < 0.001). The severity of pain there was no statistical difference in both groups before, the first, and the second weeks after the intervention, (p > 0.05); however, in the third and fourth weeks after the intervention, the mean severity of pain in the eucalyptus group was lower than in the control group, and these differences were statistically significant between the two groups (p < 0.05). Also, the patients' quality of life in the eucalyptus group was increased significantly (P < 0.001).

CONCLUSION

The eucalyptus leads to pain reduction, and consequently, improves the quality of life of patients with rheumatoid arthritis.

TRIAL REGISTRATION

IRCT20160110025929N15 Registration date: ; https://en.irct.ir/trial/33573.

摘要

研究问题

疼痛是类风湿性关节炎最显著的症状之一,会降低生活质量。本研究的目的是确定桉叶油对类风湿性关节炎患者疼痛及生活质量的影响。

方法

在这项随机临床试验中,通过随机抽样选取了70例类风湿性关节炎患者。桉叶油组患者每天吸入1毫升桉叶油,每次5分钟,共3次,持续1个月。对照组接受安慰剂吸入。两组均采用常规治疗。使用人口统计学问卷、数字疼痛评分量表(NRS)和生活质量量表(SF - 12)收集数据。使用第19版SPSS软件进行统计分析,并应用配对检验、卡方检验、Fisher精确检验和协方差分析。

结果

与对照组相比,桉叶油组的疼痛严重程度平均得分显著降低(P < 0.001)。干预前、干预后第一周和第二周,两组的疼痛严重程度无统计学差异(p > 0.05);然而,在干预后的第三周和第四周,桉叶油组的疼痛平均严重程度低于对照组,两组之间的这些差异具有统计学意义(p < 0.05)。此外,桉叶油组患者的生活质量显著提高(P < 0.001)。

结论

桉叶油可减轻疼痛,从而改善类风湿性关节炎患者的生活质量。

试验注册

IRCT20160110025929N15 注册日期:;https://en.irct.ir/trial/33573

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dde/9428835/5b9a15cadf67/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验