多形性胶质母细胞瘤患者中与肿瘤治疗电场相关的皮肤不良事件的管理：一项27例病例系列研究。
Management of dermatologic adverse events associated with tumor treating fields in patients with glioblastoma multiforme: A 27-case series.
作者信息
Chen Xiaoxue, Zhang Yihong, Zhao Qinqin, Bai Lan, Chen Xiaoqun, Zhou Zhihuan
机构信息
Department of Neurosurgery/Neuro-Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
出版信息
Asia Pac J Oncol Nurs. 2022 Jun 3;9(8):100095. doi: 10.1016/j.apjon.2022.100095. eCollection 2022 Aug.
OBJECTIVE
This study summarized the clinical management of 27 patients with glioblastoma multiforme who tumor treating fields therapy for the healthcare providers.
METHODS
Glioblastoma multiforme patients who experienced dermatologic adverse events after tumor treating fields therapy from April 2019 to May 2021 were included. The clinical management involved educating patients and their caregivers on the prevention of dermatologic adverse events, scalp assessment and preparation, and removal and replacement of the transducer array. Informed consent for participating in the study including the taking of pictures was obtained from all patients.
RESULTS
The dermatologic adverse events were successfully managed in all 27 patients, with no severe dermatologic adverse events were reported.
CONCLUSIONS
Data on tumor treating fields-related dermatologic adverse events is rarely reported, and published reports of management of scalp dermatologic adverse events are lacking. This case series summarizes a clinically individualized management for tumor treating fields-related dermatologic adverse events.
目的
本研究为医疗服务提供者总结了27例多形性胶质母细胞瘤患者的肿瘤治疗电场疗法的临床管理。
方法
纳入2019年4月至2021年5月在肿瘤治疗电场疗法后出现皮肤不良事件的多形性胶质母细胞瘤患者。临床管理包括对患者及其护理人员进行皮肤不良事件预防、头皮评估与准备以及换能器阵列的移除与更换方面的教育。所有患者均获得参与本研究（包括拍照）的知情同意。
结果
所有27例患者的皮肤不良事件均得到成功管理，未报告严重皮肤不良事件。
结论
关于肿瘤治疗电场相关皮肤不良事件的数据鲜有报道，且缺乏头皮皮肤不良事件管理的已发表报告。本病例系列总结了肿瘤治疗电场相关皮肤不良事件的临床个体化管理。
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