No sex-related differences in human corpus callosum based on magnetic resonance imagery.

Recent studies have reported sex-related differences in the morphology of the human corpus callosum in cadaver brains. To further investigate these reports, sagittal magnetic resonance image scans from 40 male and 40 female subjects were used to compare callosal morphology. Relative callosal measurements were calculated by morphometric analysis. Significant sex-related differences were not found for callosal areas, maximal callosal width, or callosal curvature. These results indicate the need for further study before claims of sex-related differences can be accepted.