Zaidel E, Aboitiz F, Clarke J
Department of Psychology, University of California, Los Angeles, USA.
Biol Res. 1995;28(1):27-43.
An embryogenetic hypothesis states that hemispheric specialization is inversely related to callosal connectivity (Geschwind and Galaburda, 1985). We tested this hypothesis (i) anatomically by relating postmortem planum temporale asymmetry to regional callosal morphology and (ii) behaviorally by relating the right visual field advantage in a lateralized lexical decision task with associative primes to regional callosal morphometry using magnetic resonance imaging (MRI). The postmortem study showed a significant negative correlation between planum temporale asymmetry and the number of small diameter fibers in the isthmus of the corpus callosum, but only for males. The MRI study showed a significant negative correlation between the right visual hemifield advantage for associated words and the cross section size of the isthmus of the corpus callosum, but again only in males. There was no sex difference in either the anatomical asymmetry, the behavioral asymmetry, or the callosal morphology. These convergent results suggest that there is a sexual dimorphism in interhemispheric relations in humans.
一种胚胎发生假说认为，半球特化与胼胝体连接性呈负相关（Geschwind和Galaburda，1985年）。我们通过以下方式验证了这一假说：（i）在解剖学上，将死后颞平面不对称性与区域胼胝体形态相关联；（ii）在行为学上，使用磁共振成像（MRI），将侧向化词汇判断任务中对联想启动词的右视野优势与区域胼胝体形态测量相关联。死后研究显示，颞平面不对称性与胼胝体峡部小直径纤维数量之间存在显著负相关，但仅在男性中如此。MRI研究显示，对联想词的右视野优势与胼胝体峡部横截面大小之间存在显著负相关，但同样仅在男性中如此。在解剖学不对称性、行为不对称性或胼胝体形态方面均不存在性别差异。这些趋同结果表明，人类半球间关系存在性二态性。
