与奥尔波特综合征相关的肺钙化症。

Pulmonary calcinosis associated with Alport syndrome.

作者信息

Mismetti Valentine, Perquis Marie-Pierre, Hamdi Lina, Froudarakis Marios E, Vergnon Jean-Michel

机构信息

Department of Pulmonology and Thoracic Oncology, North Hospital, University Hospital of Saint-Etienne, France.

出版信息

Respir Med Case Rep. 2022 Aug 24;39:101727. doi: 10.1016/j.rmcr.2022.101727. eCollection 2022.

DOI:10.1016/j.rmcr.2022.101727

PMID:36060641

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9428909/

Abstract

We report the case of a 48-year-old woman under dialysis from chronic renal failure (CRF) since the age of 27, due to Alport syndrome. The patient underwent routine chest X-ray on which diffuse micronodules were shown. Chest computed tomography showed partially calcified micronodules with centrilobular distribution respecting the subpleural spaces and predominant in the upper lobar regions. Metastatic pulmonary calcinosis was confirmed by the bone scan with an overall course of 29 years. This is the first reported case of pulmonary calcinosis from CRF due to Alport syndrome.

摘要

我们报告了一例48岁女性患者的病例，该患者自27岁起因阿尔波特综合征接受慢性肾衰竭（CRF）透析治疗。患者进行了常规胸部X线检查，显示有弥漫性微小结节。胸部计算机断层扫描显示部分钙化的微小结节呈小叶中心分布，累及胸膜下间隙，以上叶区域为主。骨扫描证实为转移性肺钙化，病程长达29年。这是首例因阿尔波特综合征导致的慢性肾衰竭引起肺钙化的报道病例。