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Targeted BRAF Inhibitor Therapy Induces Remission of Unresectable Ampullary Adenocarcinoma.

作者信息

Rego Rayburn, Safar Ahmed

机构信息

Department of Gastroenterology, CAVHS, Little Rock, AR.

Department of Hematology and Oncology, CAVHS, Little Rock, AR.

出版信息

ACG Case Rep J. 2022 Aug 31;9(8):e00844. doi: 10.14309/crj.0000000000000844. eCollection 2022 Aug.

DOI:10.14309/crj.0000000000000844
PMID:36061246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9433074/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/04ceefe86838/ac9-9-e00844-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/6a78a04281b1/ac9-9-e00844-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/33e38dca78d3/ac9-9-e00844-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/27e952ab824c/ac9-9-e00844-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/04ceefe86838/ac9-9-e00844-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/6a78a04281b1/ac9-9-e00844-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/33e38dca78d3/ac9-9-e00844-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/27e952ab824c/ac9-9-e00844-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c2/9433074/04ceefe86838/ac9-9-e00844-g004.jpg

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本文引用的文献

1
KRAS, NRAS and BRAF analysis of ampullary adenocarcinoma classified using CK7, CK20, MUC1 and MUC2.使用细胞角蛋白7(CK7)、细胞角蛋白20(CK20)、粘蛋白1(MUC1)和粘蛋白2(MUC2)对壶腹腺癌进行KRAS、NRAS和BRAF分析。
J Gastrointest Oncol. 2018 Oct;9(5):820-827. doi: 10.21037/jgo.2018.05.03.
2
Demographics, tumor characteristics, treatment, and clinical outcomes of patients with ampullary cancer: a Surveillance, Epidemiology, and End Results (SEER) cohort study.壶腹癌患者的人口统计学、肿瘤特征、治疗及临床结局:一项监测、流行病学和最终结果(SEER)队列研究
Minerva Gastroenterol Dietol. 2019 Jun;65(2):85-90. doi: 10.23736/S1121-421X.18.02543-6. Epub 2018 Nov 27.
3
Prognostic impact of immunohistochemical expression of CK7 and CK20 in curatively resected ampulla of Vater cancer.
CK7和CK20免疫组化表达对根治性切除的 Vater壶腹癌的预后影响
BMC Gastroenterol. 2015 Nov 24;15:165. doi: 10.1186/s12876-015-0396-x.
4
Uncommon BRAF mutations in the follicular variant of thyroid papillary carcinoma: New insights.甲状腺乳头状癌滤泡变体中罕见的BRAF突变:新见解
Cancer Cytopathol. 2015 Oct;123(10):593-602. doi: 10.1002/cncy.21586. Epub 2015 Jul 31.
5
Molecular analysis of PIK3CA, BRAF, and RAS oncogenes in periampullary and ampullary adenomas and carcinomas.壶腹周围和壶腹腺瘤及癌中PIK3CA、BRAF和RAS癌基因的分子分析。
J Gastrointest Surg. 2009 Aug;13(8):1510-6. doi: 10.1007/s11605-009-0917-4. Epub 2009 May 14.