Iversen Wm Larkin, Monroe Todd B, Atalla Sebastian, Anderson Alison R, Cowan Ronald L, Wright Kathy D, Failla Michelle D, Moss Karen O
College of Nursing, The Ohio State University, Columbus, OH, United States.
Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Front Pain Res (Lausanne). 2022 Aug 19;3:926459. doi: 10.3389/fpain.2022.926459. eCollection 2022.
Recruitment and retention of participants for pain-related neuroimaging research is challenging and becomes increasingly so when research participants have a diagnosis of Alzheimer's disease and related dementias (ADRD). This article shares the authors' recommendations from several years of successful recruitment and completion of pain-related neuroimaging studies of people living with ADRD and includes supportive literature. While not an exhaustive list, this review covers several topics related to recruitment and retention of participants living with ADRD, including community engagement, capacity to consent, dementia diagnostic criteria, pain medication and other study exclusion criteria, participant and caregiver burden, communication concerns, and relationships with neuroimaging facilities. Threaded throughout the paper are important cultural considerations. Additionally, we discuss implications of the coronavirus (COVID-19) pandemic for recruitment. Once tailored to specific research study protocols, these proven strategies may assist researchers with successfully recruiting and retaining participants living with ADRD for pain-related neuroimaging research studies toward improving overall health outcomes.
招募和留住疼痛相关神经影像学研究的参与者具有挑战性，而当研究参与者被诊断患有阿尔茨海默病及相关痴呆症（ADRD）时，这一挑战变得愈发严峻。本文分享了作者在成功招募和完成ADRD患者疼痛相关神经影像学研究的数年经验中得出的建议，并包含支持性文献。虽然并非详尽无遗的清单，但本综述涵盖了与ADRD患者招募和留住相关的几个主题，包括社区参与、同意能力、痴呆症诊断标准、止痛药物及其他研究排除标准、参与者和照料者负担、沟通问题以及与神经影像学设施的关系。贯穿全文的还有重要的文化考量因素。此外，我们讨论了冠状病毒（COVID-19）大流行对招募工作的影响。一旦针对特定的研究方案进行调整，这些经过验证的策略可能会帮助研究人员成功招募和留住ADRD患者参与疼痛相关神经影像学研究，以改善整体健康结局。
