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儿童和青少年的血铅水平、听力阈值及神经行为发育

Blood lead, hearing thresholds, and neurobehavioral development in children and youth.

作者信息

Schwartz J, Otto D

出版信息

Arch Environ Health. 1987 May-Jun;42(3):153-60. doi: 10.1080/00039896.1987.9935814.

Abstract

NHANES II audiometry data were used to confirm a previously observed link between blood lead (PbB) level and hearing threshold. Other indicators of neurological development, such as age at which a child first sat up, walked, and spoke, and the presence of speech difficulties and hyperactivity were also examined to determine if they were significantly related to lead exposure. The probability of elevated hearing thresholds at 500, 1000, 2000 and 4000 Hz increased significantly (p less than .0001) with increasing PbB for both ears. PbB levels were also significantly related to delays in the age at which children first sat up, walked, and spoke and to the probability that a child was hyperactive. Lead was not related to the probability of a child having a previously diagnosed speech impairment.

摘要

美国国家健康与营养检查调查(NHANES)II的听力测定数据被用于证实先前观察到的血铅(PbB)水平与听力阈值之间的联系。还检查了其他神经发育指标,如儿童首次坐立、行走和说话的年龄,以及是否存在语言困难和多动,以确定它们是否与铅暴露有显著关联。双耳在500、1000、2000和4000赫兹时听力阈值升高的概率随着血铅水平的升高而显著增加(p小于0.0001)。血铅水平还与儿童首次坐立、行走和说话年龄的延迟以及儿童多动的概率显著相关。铅与儿童先前被诊断为语言障碍的概率无关。

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