Arlow F L, Dekovich A A, Priest R J, Beher W T
Arch Intern Med. 1987 Jul;147(7):1327-9.
Diarrhea that develops after cholecystectomy may be due to increased amounts of bile acids presented to the large bowel, a "cholerheic enteropathy." We have studied eight patients to determine the cause for chronic diarrhea after cholecystectomy and found no abnormality other than elevated bile acids in the stool of six of them. All patients with bile acid malabsorption had daily stool weights greater than 200 g and total fecal bile acids three to ten times greater than normal. Patients responded dramatically to treatment with cholestyramine resin.
胆囊切除术后出现的腹泻可能是由于进入大肠的胆汁酸量增加，即“胆汁反流性肠病”。我们研究了8例胆囊切除术后慢性腹泻的患者，发现除其中6例患者粪便中胆汁酸升高外，无其他异常。所有胆汁酸吸收不良的患者每日粪便重量均超过200克，粪便总胆汁酸比正常水平高三至十倍。患者对考来烯胺树脂治疗反应显著。
