Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, U.S.A.
Department of Otolaryngology, Brigham and Women's Hospital, Boston, Massachusetts, U.S.A.
Laryngoscope. 2023 May;133(5):1205-1210. doi: 10.1002/lary.30363. Epub 2022 Sep 5.
To elucidate potential tissue coverage of side-firing optical fibers in office-based endoscopic laser treatment of larynx, as well as to demonstrate their enhanced ability to address challenging anatomic areas.
We performed a comparative study of four different fiber designs: a traditional forward-facing fiber, and three side-firing fibers that emit light at an angle of 45°, 70°, and 90°, respectively. The study was conducted in simulation, using eight three-dimensional models of the human larynx generated from microtomography x-ray scans. A computer program simulated the insertion of the endoscope into the larynx, and the Möller-Trumbore algorithm was used to simulate the application of laser light.
Side-firing laser fibers increased potential tissue coverage by a mean of 50.2 (standard deviation [SD] 25.8), 73.8 (SD 41.3), and 84.0 (SD 47.6) percent for angles of 45°, 70°, and 90°, respectively, compared to forward-facing fibers. Angled fibers provided access to areas of the larynx considered difficult to address by traditional methods, including the infraglottis, laryngeal ventricle, and right vocal fold.
Simulation results suggest that side-firing optical fibers have the potential to enhance anatomical access during in-office endoscopic laser procedures in the larynx. Further research is needed to better understand the benefits and any potential risks or contraindications of side-firing optical fibers.
NA Laryngoscope, 133:1205-1210, 2023.
阐明在局麻内镜激光治疗喉部疾病中,侧射光纤潜在的组织覆盖范围,并展示其增强处理挑战性解剖区域的能力。
我们对四种不同光纤设计进行了对比研究:传统的前向光纤,以及分别以 45°、70°和 90°发射光的三种侧射光纤。该研究在模拟中进行,使用从微断层 X 射线扫描生成的八个人类喉部的三维模型。计算机程序模拟了内窥镜插入喉部的过程,Möller-Trumbore 算法用于模拟激光光的应用。
与前向光纤相比,侧射激光光纤的组织覆盖面积分别增加了 50.2%(标准差 [SD] 25.8%)、73.8%(SD 41.3%)和 84.0%(SD 47.6%)。角度光纤可进入传统方法认为难以处理的喉部区域,包括会厌下区、喉室和声门下区。
模拟结果表明,侧射光纤有可能增强局麻内镜激光手术中喉部的解剖学进入。需要进一步研究以更好地了解侧射光纤的益处以及任何潜在的风险或禁忌症。
无。喉镜,133:1205-1210,2023。