Department of Radiology, Wuchuan People's Hospital, Wuchuan, China.
Department of Radiology, Xiaolan Hospital Affiliated to Southern Medical University, Zhongshan, China.
Cancer Invest. 2022 Oct;40(9):789-798. doi: 10.1080/07357907.2022.2121965. Epub 2022 Sep 14.
The present study aimed to compare prostate cancer (PCa) and clinically significant PCa (csPCa) detection sensitivity between magnetic resonance imaging guided-biopsy (MRI-GB) and transrectal ultrasound-guided biopsy (TRUS-GB) in patients with ≥ 1 negative TRUS-GB, and to explore the additive value of TRUS-GB to MRI-GB. The meta-analysis of 18 studies demonstrated that MRI-GB had a similar sensitivity for PCa detection but a higher sensitivity for csPCa than TRUS-GB. In conclusion, there was limited value in combining TRUS-GB with MRI-GB compared with MRI-GB alone for csPCa detection in patients with one or more negative TRUS-GBs that were suspicious of having PCa.
本研究旨在比较≥1 次经直肠超声引导活检（TRUS-GB）阴性的患者中，磁共振成像引导活检（MRI-GB）与经直肠超声引导活检（TRUS-GB）在前列腺癌（PCa）和临床显著前列腺癌（csPCa）检测中的敏感性，并探讨 TRUS-GB 对 MRI-GB 的附加价值。对 18 项研究的荟萃分析表明，MRI-GB 检测 PCa 的敏感性相似，但检测 csPCa 的敏感性高于 TRUS-GB。总之，对于疑似患有 PCa 且有 1 次或多次 TRUS-GB 阴性的患者，与单独使用 MRI-GB 相比，将 TRUS-GB 与 MRI-GB 联合使用对 csPCa 的检测价值有限。
