Shchegol'kov A N
Arkh Anat Gistol Embriol. 1987 Apr;92(4):41-8.
In the model experiments with physical overloading of "trained" rabbits, that repeatedly terminated in death, it has been stated that ultrastructural changes of the myocardial blood capillaries can be manifested as a considerable increase of the endotheliocytic nuclei volume, swelling of the cytoplasmic matrix, an essential accumulation of pinocytic vesicles, or a rather significant decrease of their number in cytoplasm and as various combinations of the changes mentioned; this negatively influences hemodynamic and trophic functions of the capillaries. The changes of endotheliocytes can be characterized as submicroscopical bases of the transcapillary insufficiency. More manifested ultrastructural changes of the capillaries are noted in the left cardiac parts.
在对“训练有素”的兔子进行反复导致死亡的物理超负荷模型实验中,已表明心肌毛细血管的超微结构变化可表现为内皮细胞核体积显著增加、细胞质基质肿胀、吞饮小泡大量积聚,或其在细胞质中的数量显著减少,以及上述变化的各种组合;这对毛细血管的血液动力学和营养功能产生负面影响。内皮细胞的变化可被视为跨毛细血管功能不全的亚微观基础。在心脏左侧部分观察到毛细血管更明显的超微结构变化。