Mori N, Asai H, Doi K, Matsunaga T
Audiology. 1987;26(2):103-10.
In order to examine the usefulness of the noninvasive extratympanic electrocochleography (ECochG) in the diagnosis of Menière's disease, the results of extratympanic ECochG, performed on 28 normally hearing ears, 3 ears with otosclerosis and 325 ears with sensorineural hearing loss of various origins including 56 Menière ears, were analyzed. The characteristics of summating potential (SP) parameters in Menière ears were different from those of ears with hair cell loss due to streptomycin and kanamycin ototoxicity and noise, while there was no difference between the action potential (AP) of the cochlear nerve parameters of Menière ears and ears with hair cell loss. A much higher incidence of increased-SP/AP amplitude ratios in Menière's disease was observed than in hearing loss of other origins. The results demonstrate the usefulness of noninvasive extratympanic ECochG in the diagnosis of Menière's disease.
为了研究无创性鼓室外电耳蜗图(ECochG)在梅尼埃病诊断中的应用价值,分析了对28只听力正常的耳朵、3只耳硬化症耳朵以及325只各种原因导致的感音神经性听力损失耳朵(包括56只梅尼埃病耳朵)进行鼓室外ECochG检查的结果。梅尼埃病耳朵中总和电位(SP)参数的特征与链霉素和卡那霉素耳毒性及噪声导致毛细胞损失的耳朵不同,而梅尼埃病耳朵与毛细胞损失耳朵的蜗神经动作电位(AP)参数之间没有差异。观察到梅尼埃病中SP/AP振幅比值升高的发生率远高于其他原因导致的听力损失。结果表明无创性鼓室外ECochG在梅尼埃病诊断中具有应用价值。