Chen C S, Wong Y C
Department of Otolaryngology, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1993 Nov;52(5):319-24.
In order to examine the usefulness of the electrocochleography (ECoG) in the diagnosis of Menière's disease and establish the diagnostic criteria in Chinese, transtympanic ECoG was performed on 18 normal ears, 22 Menière's ears and 14 ears with cochlear type sensorineural hearing loss other than Menière's disease. Although the Menière's ears had larger mean summating potential (SP) than the normal ears, the difference between both groups was not statistically significant. The mean amplitude and latency of the action potential (AP) in Menière's ears decreased and elongated significantly, but neither was sensitive enough in diagnosing Menière's disease. The SP/AP amplitude ratio not only made significant difference among 3 groups, but also had good diagnostic sensitivity (59.1%) and specificity (92%) in diagnosing Menière's disease while using the 95% upper confidence limit of the normative data (i.e., 34%). The SP/AP amplitude ratio of Menière's ears tended to increase while the mean hearing level of 4-8 KHz deteriorated. Also, abnormal enlargement of the SP/AP amplitude ratio in Menière's disease tended to be the result of decreased AP amplitude.
为探讨电耳蜗图(ECoG)在梅尼埃病诊断中的应用价值并建立中文诊断标准,对18只正常耳、22只梅尼埃病耳及14只非梅尼埃病的耳蜗型感音神经性聋耳进行了经鼓膜ECoG检查。虽然梅尼埃病耳的平均总和电位(SP)大于正常耳,但两组间差异无统计学意义。梅尼埃病耳的动作电位(AP)平均幅度降低、潜伏期明显延长,但两者对梅尼埃病的诊断均不够敏感。SP/AP幅度比不仅在三组间有显著差异,且在以正常数据的95%上置信限(即34%)作为诊断标准时,对梅尼埃病的诊断具有良好的敏感性(59.1%)和特异性(92%)。梅尼埃病耳的SP/AP幅度比随4 - 8kHz平均听力水平下降而有升高趋势。此外,梅尼埃病中SP/AP幅度比异常增大往往是AP幅度降低的结果。