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严重创伤性脑损伤的发生率、损伤机制和死亡率:来自新西兰和挪威的观察性基于人群队列研究。

Incidence, Mechanisms of Injury and Mortality of Severe Traumatic Brain Injury: An Observational Population-Based Cohort Study from New Zealand and Norway.

机构信息

Department of Neurosurgery, Stavanger University Hospital, PO Box 8100, 4068, Stavanger, Norway.

Department of Quality and Health Technology, University of Stavanger, Stavanger, Norway.

出版信息

World J Surg. 2022 Dec;46(12):2850-2857. doi: 10.1007/s00268-022-06721-8. Epub 2022 Sep 5.

Abstract

BACKGROUND

Comparing trauma registry data from different countries can help to identify possible differences in epidemiology, which may help to improve the care of trauma patients.

METHODS

This study directly compares the incidence, mechanisms of injuries and mortality of severe TBI based on population-based data from the two national trauma registries from New Zealand and Norway. All patients prospectively registered with severe TBI in either of the national registries for the 4-year study period were included. Patient and injury variables were described and age-adjusted incidence and mortality rates were calculated.

RESULTS

A total of 1378 trauma patients were identified of whom 751 (54.5%) from New Zealand and 627 (45.5%) from Norway. The patient cohort from New Zealand was significantly younger (median 32 versus 53 years; p < 0.001) and more patients from New Zealand were injured in road traffic crashes (37% versus 13%; p < 0.001). The age-adjusted incidence rate of severe TBI was 3.8 per 100,000 in New Zealand and 2.9 per 100,000 in Norway. The age-adjusted mortality rates were 1.5 per 100,000 in New Zealand and 1.2 per 100,000 in Norway. The fatality rates were 38.5% in New Zealand and 34.2% in Norway (p = 0.112).

CONCLUSIONS

Road traffic crashes in younger patients were more common in New Zealand whereas falls in elderly patients were the main cause for severe TBI in Norway. The age-adjusted incidence and mortality rates of severe TBI among trauma patients are similar in New Zealand and Norway. The fatality rates of severe TBI are still considerable with more than one third of patients dying.

摘要

背景

比较来自不同国家的创伤登记数据可以帮助确定流行病学方面的差异,这可能有助于改善创伤患者的治疗效果。

方法

本研究直接比较了基于新西兰和挪威两个国家创伤登记处的基于人群数据的严重 TBI 的发生率、损伤机制和死亡率。在整个 4 年的研究期间,将所有前瞻性登记的严重 TBI 患者纳入到这两个国家创伤登记处的研究中。描述患者和损伤变量,并计算年龄调整后的发生率和死亡率。

结果

共确定了 1378 名创伤患者,其中 751 名(54.5%)来自新西兰,627 名(45.5%)来自挪威。新西兰患者队列明显更年轻(中位数 32 岁对 53 岁;p<0.001),更多的新西兰患者因道路交通碰撞而受伤(37%对 13%;p<0.001)。新西兰严重 TBI 的年龄调整发生率为每 100,000 人 3.8 例,挪威为每 100,000 人 2.9 例。新西兰和挪威的年龄调整死亡率分别为每 100,000 人 1.5 例和 1.2 例。新西兰的病死率为 38.5%,挪威为 34.2%(p=0.112)。

结论

在新西兰,年轻患者中更常见道路交通碰撞引起的创伤,而在挪威,老年患者中跌倒则是导致严重 TBI 的主要原因。新西兰和挪威创伤患者严重 TBI 的年龄调整发生率和死亡率相似。严重 TBI 的病死率仍然相当高,超过三分之一的患者死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be9/9636291/c3cff8c07158/268_2022_6721_Fig1_HTML.jpg

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