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挪威医院收治的严重创伤性脑损伤发病率和住院病死率:一项全国性队列研究。

Incidence of hospital-admitted severe traumatic brain injury and in-hospital fatality in Norway: a national cohort study.

机构信息

Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Ulleval, Oslo, Norway.

出版信息

Neuroepidemiology. 2012;38(4):259-67. doi: 10.1159/000338032. Epub 2012 Jun 5.

DOI:10.1159/000338032
PMID:22678449
Abstract

AIMS

The aims of this study were to assess the incidence of hospital-admitted severe traumatic brain injury (TBI) in the adult population in Norway, and to determine whether there were differences in the epidemiological characteristics of severe TBI between rural and urban regions.

METHODS

A prospective population-based study on adults with severe TBI admitted to the Norwegian Trauma Referral Centres during the 2-year period (2009-2010). The electronic patient register was searched weekly for ICD-10 diagnoses of intracranial injuries (S06.0-S06.9) to identify patients. Severe TBI was defined as lowest unsedated Glasgow Coma Scale Score ≤8 during the first 24 h after injury.

RESULTS

The annual age-adjusted incidence was estimated at 5.2/100,000 in 2009 and 4.1/100,000 in 2010. The highest frequency of hospitalized patients was found among the youngest and the oldest age groups. The most common causes of injury were falls and transport accidents. The highest in-hospital case-fatality rate was found among the oldest patients. There were consistent epidemiological characteristics of severe TBI from both rural and urban regions.

CONCLUSIONS

The incidence of hospital-admitted patients with severe TBI in this national study supports the declining incidence of TBI reported internationally. No major differences were found in epidemiological characteristics between the urban and rural parts of Norway.

摘要

目的

本研究旨在评估挪威成年人因严重创伤性脑损伤(TBI)住院的发生率,并确定农村和城市地区严重 TBI 的流行病学特征是否存在差异。

方法

这是一项针对在 2009-2010 年期间因严重 TBI 而被挪威创伤转诊中心收治的成年人的前瞻性基于人群的研究。每周通过电子患者登记册搜索颅内损伤的 ICD-10 诊断(S06.0-S06.9),以识别患者。严重 TBI 的定义为伤后 24 小时内最低未镇静格拉斯哥昏迷量表评分≤8。

结果

2009 年和 2010 年的年龄调整后年发病率估计分别为 5.2/100,000 和 4.1/100,000。住院患者中年龄最小和最大的年龄组频率最高。受伤最常见的原因是跌倒和交通意外。住院病死率最高的是最年长的患者。农村和城市地区严重 TBI 的流行病学特征基本一致。

结论

本项全国性研究中严重 TBI 住院患者的发病率支持国际上报道的 TBI 发病率下降。在挪威城乡地区,在流行病学特征方面未发现重大差异。

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