Monash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, Australia.
Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, Australia.
Drug Alcohol Rev. 2023 Mar;42(3):604-613. doi: 10.1111/dar.13539. Epub 2022 Sep 5.
Persistent high rates of prescription opioid use and harms remain a concern in Australia, Europe and North America. Research priority setting can inform the research agenda, strategic responses and evidence-based interventions. The objective of this study was to establish research priorities related to the safe and effective use of prescription opioids in general practice.
Consumers, clinicians and policy makers were invited to participate in a structured consensus workshop in May 2021. A modified nominal group technique was used to explore research priorities for the safe and effective use of opioids in Australian general practice. Research priorities were identified, consolidated and prioritised using a structured process.
Seventeen consumer, medical, pharmacy, nursing, allied health and policy participants generated 26 consolidated priorities across three domains: (i) consumer-focused priorities; (ii) clinician and practice-focused priorities; and (iii) system and policy-focused priorities. The highest ranked research priorities in each of the domains were consumer characteristics that influence opioid prescribing and outcomes, opioid deprescribing strategies, and system-level barriers to prescribing alternatives to opioids, in the consumer, clinician and practice, and system and policy domains, respectively.
The priorities reflect opportunities for research priority setting within Australian general practice. The priorities provide a map for future qualitative and quantitative research that will inform safe and effective opioid prescribing.
在澳大利亚、欧洲和北美，处方类阿片药物的持续高使用率和相关危害仍然令人担忧。研究重点的设定可以为研究议程、战略应对措施和循证干预措施提供信息。本研究的目的是确定与普通实践中处方类阿片药物的安全和有效使用相关的研究重点。
2021 年 5 月，邀请消费者、临床医生和政策制定者参加了一个结构化的共识研讨会。采用改良的名义群体技术来探讨澳大利亚普通实践中安全有效使用阿片类药物的研究重点。使用结构化的过程确定、整合和优先考虑研究重点。
17 名消费者、医疗、药剂、护理、联合健康和政策参与者在三个领域生成了 26 个综合重点：（i）以消费者为重点的重点；（ii）以临床医生和实践为重点的重点；（iii）以系统和政策为重点的重点。在每个领域中排名最高的研究重点分别是影响阿片类药物处方和结果的消费者特征、阿片类药物停药策略以及系统层面上替代阿片类药物处方的障碍，分别在消费者、临床医生和实践以及系统和政策领域。
这些重点反映了澳大利亚普通实践中进行研究重点设定的机会。这些重点为未来的定性和定量研究提供了一个蓝图，将为安全有效的阿片类药物处方提供信息。
