Londhe Sanjay Bhalchandra, Khot Rahul, Shah Ravi Vinod, Desouza Clevio
Hoy Spirit Hospital, Andheri, India.
Criticare Superspeciality Hospital, Andheri, Mumbai, India.
J Clin Orthop Trauma. 2022 Aug 22;33:101995. doi: 10.1016/j.jcot.2022.101995. eCollection 2022 Oct.
THA (Total hip arthroplasty) in advanced grade (grade 4) avascular necrosis (AVN) is a challenge to the treating surgeon as it affects young patients who have high functional demands and increased dislocation risk. The aim of the study was to evaluate the efficacy, survivorship, and dislocation rate of uncemented dual mobility cups (DMC) in advanced grade IV AVN young patients.
Retrospective cohort study involving 204 DMC THA for advanced grade IV AVN from January 2013 to December 2015. The sample size of the study was estimated to be 188 hips with an α error of 0.05 and β error of 0.2. Inclusion criterion was patients less than 55 years of age with advanced grade IV AVN. Patients >55 years of age, patients diagnosed with primary osteoarthritis of the hip and hip fracture were excluded from the study. 172 patients (32 with bilateral & 140 with unilateral affection) with 204 DMC THA were evaluated clinically by Harris Hip Score (HHS) and radiologically at a follow up of 60 months. P value < 0.05 was considered significant.
Mean age of the patients was 42.5 ± 5.3. Preoperative HHS was 50.6 ± 10.5. Postoperative HHS at 5 years follow up was 96.4 ± 2.6. None of the operated patient had any dislocation episode or had undergone hip revision surgery (statistically significant against historical control of 2%, p value = 0.042). The radiological evaluation at 5 years showed no signs of radiolucent lines, periprosthetic osteolysis, polyethylene wear and signs of displacement or migration of the DMC. Cumulative survivorship rate at 5 years follow up was 100% without any revision/dislocation.
Use of DMC THA in young, advanced grade IV AVN patients was found to be a reliable option showing excellent early functional results with no dislocation. Ongoing follow up of this cohort is required to confirm the maintenance of these excellent functional results at follow up in the long term.
对于晚期(4级)股骨头缺血性坏死(AVN)患者进行全髋关节置换术(THA),对主刀医生来说是一项挑战,因为这类患者较为年轻,功能需求高,且脱位风险增加。本研究的目的是评估非骨水泥双动髋臼杯(DMC)在晚期IV级AVN年轻患者中的疗效、生存率和脱位率。
回顾性队列研究,纳入2013年1月至2015年12月期间因晚期IV级AVN接受204例DMC THA手术的患者。研究样本量估计为188髋,α错误率为0.05,β错误率为0.2。纳入标准为年龄小于55岁的晚期IV级AVN患者。年龄>55岁、诊断为原发性髋骨关节炎和髋部骨折的患者被排除在研究之外。对172例患者(32例双侧病变和140例单侧病变)的204例DMC THA进行了临床Harris髋关节评分(HHS)评估,并在60个月的随访中进行了影像学评估。P值<0.05被认为具有统计学意义。
患者的平均年龄为42.5±5.3岁。术前HHS为50.6±10.5。5年随访时的术后HHS为96.4±2.6。所有接受手术的患者均未发生脱位事件或接受髋关节翻修手术(与2%的历史对照相比具有统计学意义,P值=0.042)。5年时的影像学评估未显示透光线、假体周围骨溶解、聚乙烯磨损以及DMC移位或迁移的迹象。5年随访时的累积生存率为100%,无任何翻修/脱位情况。
在年轻的晚期IV级AVN患者中使用DMC THA是一种可靠选择,早期功能结果优异,无脱位情况。需要对该队列进行持续随访,以确认长期随访中这些优异功能结果能否维持。