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在长期遭受歧视和社会挫败的人群中,精神分裂症的解离和误诊。

Dissociation and misdiagnosis of schizophrenia in populations experiencing chronic discrimination and social defeat.

机构信息

Heather Hall MD LLC, Elk Grove, California, USA.

出版信息

J Trauma Dissociation. 2024 May-Jun;25(3):334-348. doi: 10.1080/15299732.2022.2120154. Epub 2022 Sep 5.

Abstract

As recently as the late 20 century, Schizophrenia, a category of mental illness with widely varying phenotypic symptoms, was believed by psychobiologists to be a genetically based disorder in which the environment played a limited etiological role. Yet a growing body of evidence indicates a strong correlation between schizophrenia and environmental factors. This theoretical paper explores the relationship between highly elevated rates of schizophrenia in some low-income minority communities worldwide and trauma-related dissociative symptoms that often mimic schizophrenia. Elevated rates of schizophrenia in racially and ethnically isolated, inner-city Black populations are well documented. This paper contains evidence proposing that this amplification in the rate of schizophrenia is mediated by childhood trauma, disorganized attachment, and social defeat. Further, evidence demonstrating how these three variables combine in early childhood to incubate dissociative disorders will also be conveyed. The misdiagnosis of dissociative disorders as schizophrenia is theorized to partially mediate the increased rate of schizophrenia in communities that experience high levels of racial/ethnic discrimination. It is argued that this misdiagnosis is often attributable to cultural misunderstanding and/or a lack of knowledge about dissociative disorders.

摘要

直到 20 世纪后期,精神分裂症作为一种具有广泛不同表型症状的精神疾病类别,被精神生物学家认为是一种基于遗传的疾病,其中环境只起到有限的病因作用。然而,越来越多的证据表明精神分裂症与环境因素之间存在很强的相关性。这篇理论论文探讨了在世界上一些低收入少数民族社区中精神分裂症发病率极高,以及与创伤相关的分离症状(这些症状经常与精神分裂症类似)之间的关系。种族和民族隔离的城市内黑人人口中精神分裂症发病率极高的情况已得到充分记录。本文提供的证据表明,这种精神分裂症发病率的增加是由儿童时期的创伤、组织混乱的依恋关系和社会挫败感所介导的。此外,还将传达证明这三个变量如何在幼儿时期结合起来孵育分离障碍的证据。将分离障碍误诊为精神分裂症被认为部分解释了在经历高水平种族/民族歧视的社区中精神分裂症发病率的增加。有人认为,这种误诊往往归因于文化误解和/或对分离障碍缺乏了解。

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