Department of Dermatology, Venereology and Leprology, All India Institute of Medical Sciences, Rajkot, India.
J Cosmet Dermatol. 2022 Nov;21(11):5527-5531. doi: 10.1111/jocd.15324. Epub 2022 Sep 20.
There have been various treatment modalities available for alopecia in the form of topical and systemic with a variable response. The compliance of the patients is important in reaping results in alopecia. Minoxidil has come a long-way finding its use from topical formulations to systemic at lower dose in different alopecia.
The objective of this article is to discuss various conditions in alopecia where oral minoxidil has found its role.
A comprehensive literature search was performed relating to oral minoxidil role in various alopecia. Various clinical trials, case series, and case reports were searched on PubMed and Google Scholar. The references of available studies were also reviewed to collect the additional resources. Available data from various studies and case reports were collected and consolidated to provide a concise overview of oral minoxidil indications in various alopecia.
Oral minoxidil has been used in various non-scarring and scarring alopecia at a lower dosage with less side effects and with promising results. Androgenetic alopecia and female pattern hair loss were the two conditions where it has been used more commonly than other alopecia, providing a ray of hope along with overcoming the issues related to topical formulations and compliance.
目前有多种治疗脱发的方法，包括局部和全身治疗，疗效不一。患者的依从性对于治疗脱发的效果很重要。米诺地尔历经发展，从局部制剂到低剂量全身用药，已广泛应用于各种脱发。
本文旨在讨论米诺地尔在各种脱发中的应用。
对涉及米诺地尔在各种脱发中作用的文献进行了全面检索。在 PubMed 和 Google Scholar 上搜索了各种临床试验、病例系列和病例报告。还查阅了现有研究的参考文献，以收集更多资源。收集了来自各种研究和病例报告的现有数据，并进行了整合，以提供米诺地尔在各种脱发中的适应证的简明概述。
米诺地尔已在多种非瘢痕性和瘢痕性脱发中以较低剂量使用，副作用较少，且疗效较好。雄激素性脱发和女性型脱发是其比其他脱发更常用的两种情况，为克服与局部制剂和依从性相关的问题提供了一线希望。
