支撑在多孔滤纸上的稳定磷脂膜。

Stable phospholipid membrane supported on porous filter paper.

作者信息

Yoshikawa K, Hayashi H, Shimooka T, Terada H, Ishii T

出版信息

Biochem Biophys Res Commun. 1987 Jun 30;145(3):1092-7. doi: 10.1016/0006-291x(87)91549-x.

Abstract

A novel method to construct a stable and uniform phospholipid membrane of large area and good manipulability is reported. Using the Langmuir-Blodgett (LB) technique, a monolayer of phospholipid can be transferred to filter paper. The electrical conductance across the pores of the lipid membrane is about 1.8 X 10(-9) S/cm2, corresponding to the conductance of 10(-7)-10(-10) S/cm2 reported for bilayer lipid membranes (BLM) of phospholipids. A scanning electron micrograph demonstrated that the phospholipid membrane on the filter paper was uniform.

摘要

报道了一种构建大面积、具有良好可操作性的稳定且均匀的磷脂膜的新方法。利用朗缪尔-布洛杰特（LB）技术，可将单层磷脂转移至滤纸上。跨脂质膜孔隙的电导约为1.8×10⁻⁹ S/cm²，这与报道的磷脂双层脂质膜（BLM）的10⁻⁷ - 10⁻¹⁰ S/cm²的电导相对应。扫描电子显微镜照片显示滤纸上的磷脂膜是均匀的。