鼻眶毛霉菌病
Rhino-orbital mucormycosis.
作者信息
Ryu Byoung U, Laylani Noor Adnan Rashid, Davila-Siliezar Pamela, Lee Andrew G
机构信息
McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas.
出版信息
Curr Opin Ophthalmol. 2022 Nov 1;33(6):501-506. doi: 10.1097/ICU.0000000000000892. Epub 2022 Aug 24.
PURPOSE OF REVIEW
The current article will update and review the clinical and radiological manifestations and management of rhino-orbital mucormycosis (ROM).
RECENT FINDINGS
There has been an increase in cases of ROM worldwide, especially in India. Immunosuppression (especially diabetes mellitus) is a known predisposing risk factor for ROM. Delayed diagnosis and treatment of ROM can be vision or life-threatening. This article reviews the clinical and radiologic features, treatment, and prognosis of ROM with special emphasis on new and emerging therapies.
SUMMARY
ROM is an angioinvasive fungal infection that affects the sinuses and orbits and may present to ophthalmologists. Clinicians should have a high index of suspicion for ROM, especially in patients with poorly controlled diabetes mellitus or other immunosuppression. Corticosteroid treatment (including the recent COVID-19 pandemic) may be a predisposing risk factor for ROM.
综述目的
本文将更新并回顾鼻眶毛霉菌病（ROM）的临床和影像学表现及治疗方法。
最新发现
全球范围内ROM病例有所增加，尤其是在印度。免疫抑制（尤其是糖尿病）是已知的ROM易感风险因素。ROM的延迟诊断和治疗可能会危及视力或生命。本文回顾了ROM的临床和放射学特征、治疗及预后，特别强调了新出现的治疗方法。
总结
ROM是一种血管侵袭性真菌感染，可累及鼻窦和眼眶，可能会被眼科医生发现。临床医生应对ROM保持高度怀疑，尤其是对糖尿病控制不佳或有其他免疫抑制情况的患者。皮质类固醇治疗（包括近期的新冠疫情期间）可能是ROM的易感风险因素。
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