Dept. of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Dept. of Pharmacy, Federico II University, Naples, Italy.
Diabetes Res Clin Pract. 2022 Sep;191:110071. doi: 10.1016/j.diabres.2022.110071. Epub 2022 Sep 5.
We performed an umbrella review of dose-response meta-analyses of prospective studies reporting the incidence of type 2 diabetes associated with the consumption of animal-based foods. A systematic search was conducted in PubMed, Web of Science, Scopus, and Embase according to PRISMA. Thirteen meta-analyses are included in the study providing 175 summary risk ratio estimates. The consumption of 100 g/day of total or red meat, or 50 g/day of processed meat, were associated with an increased risk; RR and 95 % CI were respectively 1.20, 1.13-1.27; 1.22, 1.14-1.30 and 1.30, 1.22-1.39. White meat (50 g/day) was associated with an increased risk, but of lesser magnitude (RR 1.04, 95 % CI 1.00-1.08). A risk reduction was reported for 200 g/day of total dairy (RR 0.95, 95 % CI 0.92-0.98) or low-fat dairy (RR 0.96, 95 % CI 0.92-1.00) or milk (RR 0.90, 95 % CI 0.83-0.98), or 100 g/day of yogurt (RR 0.94, 95 % CI 0.90-0.98). No association with diabetes risk was reported for fish or eggs. In conclusions animal-based foods have a different association with diabetes risk. To reduce diabetes risk the consumption of red and processed meat should be restricted; a moderate consumption of dairy foods, milk and yogurt, can be encouraged; moderate amounts of fish and eggs are allowed.
我们对前瞻性研究中报告与动物源性食品消费相关的 2 型糖尿病发病率的剂量-反应荟萃分析进行了伞式审查。根据 PRISMA 进行了系统的 PubMed、Web of Science、Scopus 和 Embase 搜索。该研究纳入了 13 项荟萃分析,提供了 175 项汇总风险比估计值。每天食用 100 克总肉或红肉,或 50 克加工肉,与风险增加相关;RR 和 95%CI 分别为 1.20、1.13-1.27;1.22、1.14-1.30 和 1.30、1.22-1.39。每天食用 50 克白肉(白肉)与风险增加相关,但程度较小(RR 1.04,95%CI 1.00-1.08)。报告称,每天摄入 200 克总乳制品(RR 0.95,95%CI 0.92-0.98)或低脂乳制品(RR 0.96,95%CI 0.92-1.00)或牛奶(RR 0.90,95%CI 0.83-0.98),或每天摄入 100 克酸奶(RR 0.94,95%CI 0.90-0.98),与糖尿病风险降低相关。鱼类或鸡蛋与糖尿病风险无关联。总之,动物源性食品与糖尿病风险的关联不同。为了降低糖尿病风险,应限制食用红肉类和加工肉类;应鼓励适度摄入乳制品、牛奶和酸奶;允许适量食用鱼类和鸡蛋。