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不同动物源性食物的摄入与 2 型糖尿病风险:前瞻性研究荟萃分析的伞式评价。

Consumption of different animal-based foods and risk of type 2 diabetes: An umbrella review of meta-analyses of prospective studies.

机构信息

Dept. of Clinical Medicine and Surgery, Federico II University, Naples, Italy.

Dept. of Pharmacy, Federico II University, Naples, Italy.

出版信息

Diabetes Res Clin Pract. 2022 Sep;191:110071. doi: 10.1016/j.diabres.2022.110071. Epub 2022 Sep 5.

DOI:10.1016/j.diabres.2022.110071
PMID:36067917
Abstract

We performed an umbrella review of dose-response meta-analyses of prospective studies reporting the incidence of type 2 diabetes associated with the consumption of animal-based foods. A systematic search was conducted in PubMed, Web of Science, Scopus, and Embase according to PRISMA. Thirteen meta-analyses are included in the study providing 175 summary risk ratio estimates. The consumption of 100 g/day of total or red meat, or 50 g/day of processed meat, were associated with an increased risk; RR and 95 % CI were respectively 1.20, 1.13-1.27; 1.22, 1.14-1.30 and 1.30, 1.22-1.39. White meat (50 g/day) was associated with an increased risk, but of lesser magnitude (RR 1.04, 95 % CI 1.00-1.08). A risk reduction was reported for 200 g/day of total dairy (RR 0.95, 95 % CI 0.92-0.98) or low-fat dairy (RR 0.96, 95 % CI 0.92-1.00) or milk (RR 0.90, 95 % CI 0.83-0.98), or 100 g/day of yogurt (RR 0.94, 95 % CI 0.90-0.98). No association with diabetes risk was reported for fish or eggs. In conclusions animal-based foods have a different association with diabetes risk. To reduce diabetes risk the consumption of red and processed meat should be restricted; a moderate consumption of dairy foods, milk and yogurt, can be encouraged; moderate amounts of fish and eggs are allowed.

摘要

我们对前瞻性研究中报告与动物源性食品消费相关的 2 型糖尿病发病率的剂量-反应荟萃分析进行了伞式审查。根据 PRISMA 进行了系统的 PubMed、Web of Science、Scopus 和 Embase 搜索。该研究纳入了 13 项荟萃分析,提供了 175 项汇总风险比估计值。每天食用 100 克总肉或红肉,或 50 克加工肉,与风险增加相关;RR 和 95%CI 分别为 1.20、1.13-1.27;1.22、1.14-1.30 和 1.30、1.22-1.39。每天食用 50 克白肉(白肉)与风险增加相关,但程度较小(RR 1.04,95%CI 1.00-1.08)。报告称,每天摄入 200 克总乳制品(RR 0.95,95%CI 0.92-0.98)或低脂乳制品(RR 0.96,95%CI 0.92-1.00)或牛奶(RR 0.90,95%CI 0.83-0.98),或每天摄入 100 克酸奶(RR 0.94,95%CI 0.90-0.98),与糖尿病风险降低相关。鱼类或鸡蛋与糖尿病风险无关联。总之,动物源性食品与糖尿病风险的关联不同。为了降低糖尿病风险,应限制食用红肉类和加工肉类;应鼓励适度摄入乳制品、牛奶和酸奶;允许适量食用鱼类和鸡蛋。

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