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短期致动脉粥样硬化饮食的自发性高血压大鼠脑动脉内膜病变的延迟发展(透射电镜观察)

Delayed development of intimal lesions in cerebral arteries of spontaneously hypertensive rats subjected to a short-term atherogenic diet (TEM observations).

作者信息

Weber G, Alessandrini C, Centi L, Gerli R, Novelli M T, Petrelli L, Resi L, Salvi M, Tanganelli P

出版信息

Appl Pathol. 1986;4(4):233-6.

PMID:3606884
Abstract

In adult spontaneously hypertensive rats, subjected to an atherogenic diet (2% cholic acid in a 5% hypercholesterolic diet) for 19 weeks both aortic and carotid artery lesions were already detectable on TEM examination while the cerebral arteries did not show any lesions. Similar findings have been previously obtained in rabbits and in monkeys on atherogenic diets.

摘要

在成年自发性高血压大鼠中,给予致动脉粥样硬化饮食(5%高胆固醇饮食中含2%胆酸)19周后,透射电镜检查已可检测到主动脉和颈动脉病变,而脑动脉未显示任何病变。先前在给予致动脉粥样硬化饮食的兔子和猴子中也得到了类似的结果。

相似文献

1
Delayed development of intimal lesions in cerebral arteries of spontaneously hypertensive rats subjected to a short-term atherogenic diet (TEM observations).短期致动脉粥样硬化饮食的自发性高血压大鼠脑动脉内膜病变的延迟发展(透射电镜观察)
Appl Pathol. 1986;4(4):233-6.
2
[Preliminary observations, at the ultrastructural level, on the reactivity of cerebral arteries from New Zealand rabbits to combined atherogenic stimuli (hypercholesterol diet and hypertension)].
Boll Soc Ital Biol Sper. 1984 Mar 30;60(3):553-9.
3
An ultrastructural comparison of diet-induced atherosclerosis of arteries supplying the central nervous system in cynomolgus and rhesus monkeys.食蟹猴和恒河猴中枢神经系统供血动脉饮食诱导动脉粥样硬化的超微结构比较。
Appl Pathol. 1983;1(3):121-38.
4
Delayed intimal lesion development in cerebral arteries versus aortic and carotid arteries of spontaneously hypertensive rats.自发性高血压大鼠脑动脉与主动脉和颈动脉内膜病变发展的延迟情况。
Exp Mol Pathol. 1986 Jun;44(3):340-3. doi: 10.1016/0014-4800(86)90047-x.
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Delayed experimental atherosclerotic involvement of cerebral arteries in monkeys and rabbits (light, sem and tem observations).猴子和兔子大脑动脉的实验性动脉粥样硬化延迟累及(光镜、扫描电镜和透射电镜观察)
Pathol Res Pract. 1985 Oct;180(4):353-5. doi: 10.1016/S0344-0338(85)80105-9.
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Pathological observation of brain arteries and spontaneous aneurysms in hypertensive rats.高血压大鼠脑动脉及自发性动脉瘤的病理观察
Chin Med J (Engl). 2003 Mar;116(3):424-7.
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[Influence of long-term antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR--protective effect of nicardipine hydrochloride].
No To Shinkei. 1987 Feb;39(2):175-82.
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Prevention of stroke and preservation of the functions of cerebral arteries by treatment with perindopril in stroke-prone spontaneously hypertensive rats.培哚普利治疗易卒中型自发性高血压大鼠预防卒中及保护脑动脉功能的研究
Can J Physiol Pharmacol. 1998 Jan;76(1):26-34.
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Ultrastructural aspects of cynomolgus atherosclerotic carotid artery lesions on cholestyramine 'regression' treatment.
Appl Pathol. 1986;4(4):225-32.
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Pathological changes of cerebral vessel endothelial cells in spontaneously hypertensive rats, with special reference to the role of these cells in the development of hypertensive cerebrovascular lesions.自发性高血压大鼠脑血管内皮细胞的病理变化,特别提及这些细胞在高血压性脑血管病变发展中的作用。
Adv Neurol. 1978;20:359-69.

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