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猴子和兔子大脑动脉的实验性动脉粥样硬化延迟累及(光镜、扫描电镜和透射电镜观察)

Delayed experimental atherosclerotic involvement of cerebral arteries in monkeys and rabbits (light, sem and tem observations).

作者信息

Weber G

出版信息

Pathol Res Pract. 1985 Oct;180(4):353-5. doi: 10.1016/S0344-0338(85)80105-9.

DOI:10.1016/S0344-0338(85)80105-9
PMID:4070068
Abstract

In monkeys (Rhesus and Cynomolgus) and in rabbits on atherogenic diets, the experimental atherosclerotic involvement of cerebral arteries is strongly delayed. When extracranial arteries appear already heavily involved, no or minimal involvement of intracranial arteries is found even at scanning and/or transmission EM examination. The Concanavalin A reactivity, which is positive at the endothelial cell surface in other arterial districts, is lacking in the cerebral arteries of monkeys and rabbits. The possible significance of these findings is evaluated.

摘要

在喂食致动脉粥样化饮食的猴子(恒河猴和食蟹猴)和兔子中,脑动脉的实验性动脉粥样硬化累及情况被显著延迟。当颅外动脉已明显受累时,即使在扫描和/或透射电镜检查中,也未发现颅内动脉受累或仅有轻微受累。在其他动脉区域内皮细胞表面呈阳性的伴刀豆球蛋白A反应性,在猴子和兔子的脑动脉中并不存在。对这些发现的可能意义进行了评估。

相似文献

1
Delayed experimental atherosclerotic involvement of cerebral arteries in monkeys and rabbits (light, sem and tem observations).猴子和兔子大脑动脉的实验性动脉粥样硬化延迟累及(光镜、扫描电镜和透射电镜观察)
Pathol Res Pract. 1985 Oct;180(4):353-5. doi: 10.1016/S0344-0338(85)80105-9.
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[Preliminary data on the different endothelial reaction to Con A at different levels of the arterial tree in rabbits and in Cynomolgus monkeys].[家兔和食蟹猴动脉树不同水平对刀豆球蛋白A的不同内皮反应的初步数据]
Boll Soc Ital Biol Sper. 1981 Nov 15;57(21):2176-8.
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[Preliminary observations, at the ultrastructural level, on the reactivity of cerebral arteries from New Zealand rabbits to combined atherogenic stimuli (hypercholesterol diet and hypertension)].
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An ultrastructural comparison of diet-induced atherosclerosis of arteries supplying the central nervous system in cynomolgus and rhesus monkeys.食蟹猴和恒河猴中枢神经系统供血动脉饮食诱导动脉粥样硬化的超微结构比较。
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Delayed development of intimal lesions in cerebral arteries of spontaneously hypertensive rats subjected to a short-term atherogenic diet (TEM observations).短期致动脉粥样硬化饮食的自发性高血压大鼠脑动脉内膜病变的延迟发展(透射电镜观察)
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A morphological study of experimental cerebral atherosclerosis in rhesus monkeys.恒河猴实验性脑动脉粥样硬化的形态学研究
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Histochemical detection and quantification of macrophages in rhesus and cynomolgus monkey atherosclerotic lesions.
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Vasculature of the dental pulp of atherosclerotic monkeys: light and electron microscopic findings.动脉粥样硬化猴牙髓的血管系统:光镜和电镜观察结果
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