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四乙基铅给药后家兔尿中二乙基铅排泄的动力学

Dynamics of diethyllead excretion in the urine of rabbits after tetraethyllead administration.

作者信息

Kozarzewska Z, Chmielnicka J

出版信息

Br J Ind Med. 1987 Jun;44(6):417-21. doi: 10.1136/oem.44.6.417.

Abstract

The dynamics of diethyllead excretion in rabbit urine according to the dose and method of administration of tetraethyllead were studied. Investigations were made on male rabbits which were given two doses of tetraethyllead (12 mg/kg and 3 mg/kg) using intravenous and intragastric methods. Rabbits were also exposed for five hours to tetraethyllead at a concentration of 200 micrograms/m3 in the air. The results show the relation of the diethyllead excretion in rabbit urine to the dose and method of administration.

摘要

根据四乙基铅的剂量和给药方法,研究了兔尿中二乙基铅的排泄动态。对雄性兔进行了研究,这些兔通过静脉注射和胃内给药两种方式给予两剂四乙基铅(12毫克/千克和3毫克/千克)。兔还在空气中以200微克/立方米的浓度暴露于四乙基铅5小时。结果显示了兔尿中二乙基铅排泄与剂量和给药方法之间的关系。

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