Systems and Biomedical Engineering Department, Faculty of Engineering, Cairo University, Giza, Egypt.
Neurology Department, Faculty of Medicine, Cairo University, Giza, Egypt.
Biomed Eng Online. 2022 Sep 7;21(1):65. doi: 10.1186/s12938-022-01036-0.
Facial paralysis (FP) is an inability to move facial muscles voluntarily, affecting daily activities. There is a need for quantitative assessment and severity level classification of FP to evaluate the condition. None of the available tools are widely accepted. A comprehensive FP evaluation system has been developed by the authors. The system extracts real-time facial animation units (FAUs) using the Kinect V2 sensor and includes both FP assessment and classification. This paper describes the development and testing of the FP classification phase. A dataset of 375 records from 13 unilateral FP patients and 1650 records from 50 control subjects was compiled. Artificial Intelligence and Machine Learning methods are used to classify seven FP categories: the normal case and three severity levels: mild, moderate, and severe for the left and right sides. For better prediction results (Accuracy = 96.8%, Sensitivity = 88.9% and Specificity = 99%), an ensemble learning classifier was developed rather than one weak classifier. The ensemble approach based on SVMs was proposed for the high-dimensional data to gather the advantages of stacking and bagging. To address the problem of an imbalanced dataset, a hybrid strategy combining three separate techniques was used. Model robustness and stability was evaluated using fivefold cross-validation. The results showed that the classifier is robust, stable and performs well for different train and test samples. The study demonstrates that FAUs acquired by the Kinect sensor can be used in classifying FP. The developed FP assessment and classification system provides a detailed quantitative report and has significant advantages over existing grading scales.
面瘫(FP)是一种无法自主运动面部肌肉的疾病,影响日常活动。需要对面瘫进行定量评估和严重程度分级,以评估病情。但现有的工具都没有得到广泛认可。作者开发了一种全面的 FP 评估系统。该系统使用 Kinect V2 传感器提取实时面部动画单元(FAU),并包括 FP 评估和分类。本文介绍了 FP 分类阶段的开发和测试。作者从 13 名单侧 FP 患者中收集了 375 份记录,从 50 名对照者中收集了 1650 份记录。使用人工智能和机器学习方法对七种 FP 类别进行分类:正常病例和左右两侧的三个严重程度级别:轻度、中度和重度。为了获得更好的预测结果(Accuracy=96.8%,Sensitivity=88.9%和 Specificity=99%),开发了一种基于 SVM 的集成学习分类器,而不是一个弱分类器。针对高维数据,提出了基于 SVM 的集成方法来结合堆叠和装袋的优势。为了解决数据集不平衡的问题,使用了三种独立技术的混合策略。使用五重交叉验证评估模型的稳健性和稳定性。结果表明,该分类器稳健、稳定,对不同的训练和测试样本表现良好。研究表明,Kinect 传感器采集的 FAU 可用于 FP 分类。开发的 FP 评估和分类系统提供了详细的定量报告,与现有的分级量表相比具有显著优势。