Radtanajiravong Lalita, Peters Jake, Hummell Jake, Díez-González Silvia
Imperial College London, Department of Chemistry, MSRH, 82 Wood Lane, London W12 0BZ, UK.
Org Biomol Chem. 2022 Sep 21;20(36):7338-7342. doi: 10.1039/d2ob01259f.
Commercially available (aqueous) hypophosphorus acid is an efficient catalyst for the synthesis of α,β-unsaturated carbonyl compounds from their corresponding propargylic alcohols. Reactions were carried out in technical toluene in the presence of air and in several instances the desired products were isolated analytically pure after a simple work-up.
市售（水性）次磷酸是一种由相应的炔丙醇合成α,β-不饱和羰基化合物的高效催化剂。反应在工业甲苯中于空气存在下进行，在一些情况下，经过简单的后处理后可分离得到分析纯的所需产物。
