作为年龄、身高和体重的超越函数的肺功能发育的参考值和建模。

Reference values and modelling of lung function development as a transcendent function of age, body height and mass.

作者信息

Kristufek P, Brezina M, Ciutti P, Strmen J, Mayer M

出版信息

Bull Eur Physiopathol Respir. 1987 Mar-Apr;23(2):139-47.

Abstract

We present new lung function reference values based on an investigation of 1024 healthy subjects aged 6-81 years. The dependent variables, i.e. VC, FEV1, RV, FRC, TLC, PEF, MEF50 and MEF25 are expressed as transcendent functions of age, body height and mass. A single equation covers the age range from 6 to 81 years and reflects certain phenomena such as growth, maturation, ageing, sex differences and the undermass-overmass effect. This allows a more accurate determination of individualized reference values and normal limits.

摘要

我们基于对1024名年龄在6至81岁的健康受试者的调查，提出了新的肺功能参考值。因变量，即肺活量（VC）、第一秒用力呼气容积（FEV1）、残气量（RV）、功能残气量（FRC）、肺总量（TLC）、呼气峰值流速（PEF）、最大呼气中期流速50%（MEF50）和最大呼气中期流速25%（MEF25），表示为年龄、身高和体重的超越函数。一个单一方程涵盖了6至81岁的年龄范围，并反映了诸如生长、成熟、衰老、性别差异和体重不足-超重效应等特定现象。这使得能够更准确地确定个体化参考值和正常限度。