Shin Hangsik
Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Psychophysiology. 2023 Feb;60(2):e14173. doi: 10.1111/psyp.14173. Epub 2022 Sep 8.
Unlike traditional pulse transit time (PTT), continuous PTT (CPTT) can be used to calculate PTT from all samples within the cardiac cycle. It has the potential to be utilized for continuous blood pressure (BP) estimation. This study evaluated the feasibility of CPTT as a non-invasive consecutive blood pressure estimation method in 20 volunteers. The CPTT was calculated with a time delay in all discrete samples of photoplethysmograms measured at two different body sites. BP was then calculated with a regression equation. For comparative evaluation, BP based on PTT was also estimated. Continuous blood pressure was measured using a non-invasive volume clamp BP monitoring device. Four types of BP measurement, systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP), were estimated using PTT and CPTT. Correlation coefficients and root-mean-squared-error (RMSE) were used for evaluating BP estimation performance. For estimating SBP, DBP, PP, and MAP, PTT-based BP estimation showed correlations of .407, .373, .410, and .286, respectively, and CPTT-based BP estimation showed correlations of .436, .446, .506, and .097, respectively. With PTT-based estimation, the RMSE between the estimated BP and the baseline BP was 5.44 ± 1.56 mmHg for SBP, 3.14 ± 0.46 mmHg for DBP, 3.66 ± 0.70 mmHg for MAP, and 3.73 ± 1.31 mmHg for PP. The estimated BP using CPTT showed RMSE of 5.36 ± 1.39 mmHg for SBP, 3.02 ± 0.49 mmHg for SBP, 3.44 ± 0.63 mmHg for MAP, and 3.91 ± 1.41 mmHg for PP.
与传统脉搏传输时间（PTT）不同，连续PTT（CPTT）可用于计算心动周期内所有样本的PTT。它有潜力用于连续血压（BP）估计。本研究评估了CPTT作为一种无创连续血压估计方法在20名志愿者中的可行性。CPTT是通过在两个不同身体部位测量的光电容积脉搏波图的所有离散样本中的时间延迟来计算的。然后用回归方程计算血压。为了进行比较评估，还估计了基于PTT的血压。使用无创容积钳血压监测设备测量连续血压。使用PTT和CPTT估计了四种类型的血压测量值，即收缩压（SBP）、舒张压（DBP）、平均动脉压（MAP）和脉压（PP）。相关系数和均方根误差（RMSE）用于评估血压估计性能。对于SBP、DBP、PP和MAP的估计，基于PTT的血压估计的相关性分别为0.407、0.373、0.410和0.286，基于CPTT的血压估计的相关性分别为0.436、0.446、0.506和0.097。基于PTT的估计中，估计血压与基线血压之间的RMSE对于SBP为5.44±1.56mmHg，对于DBP为3.14±0.46mmHg，对于MAP为3.66±0.70mmHg，对于PP为3.73±1.31mmHg。使用CPTT估计的血压显示，SBP的RMSE为5.36±1.39mmHg，SBP为3.02±0.49mmHg，MAP为3.44±0.63mmHg，PP为3.91±1.41mmHg。
