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使用电子射野剂量仪对植入脊柱内固定装置的患者进行立体定向体部放射治疗的剂量验证。

Transit dosimetry of stereotactic body radiotherapy treatments with electronic portal dosimetry device in patient with spinal implant.

作者信息

Yedekci Yagiz, Elmalı Aysenur, Demirkiran Gökhan, Ozyigit Gokhan, Yazici Gözde

机构信息

Department of Radiation Oncology, Faculty of Medicine, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Hacettepe University, Sihhiye, Ankara, Turkey.

出版信息

Phys Eng Sci Med. 2022 Dec;45(4):1103-1109. doi: 10.1007/s13246-022-01177-5. Epub 2022 Sep 8.

Abstract

In recent years, the use of the Electronic Portal Imaging Device (EPID) as an in vivo dosimeter has become widespread. However, reports of EPID for stereotactic body radiotherapy (SBRT) applications is scarce. There is no data on this topic especially when there are high-density materials in the radiation field. In this study, we aimed to investigate the dose distributions of SBRT treatment plans in patients with spinal implants by transit EPID dosimetry. Implants were inserted in phantoms that mimic the vertebrae, and VMAT plans were created on the phantoms to deliver 16 Gy radiation doses to the target in 1 fraction. Transit EPID measurements were performed for each irradiation. The results were compared with the treatment planning system using the gamma analysis method. According to the gamma analysis results, while the non-implant model met the acceptance criteria with a rate of 95.4%, the implanted models did not pass the test with results between the rates of 70% to 73%. In addition, while the dose difference in the isocenter was 1.3% for the non-implanted model, this difference was observed to be between 7 and 8% in the implanted models. Our study revealed that EPID can be used as transit dosimetry for the VMAT-SBRT applications. However, unacceptable dose differences were obtained by transit EPID dosimetry in the VMAT-SBRT applications of patients with an implant. In the treatment of such patients, alternative treatment methods should be preferred in which the interaction of the implants with radiation can be prevented.

摘要

近年来,电子射野影像装置(EPID)作为一种体内剂量仪的应用已变得十分广泛。然而,关于EPID在立体定向体部放射治疗(SBRT)应用方面的报道却很少。尤其当辐射野中存在高密度物质时,关于这个主题尚无数据。在本研究中,我们旨在通过传输EPID剂量测定法来研究脊柱植入物患者SBRT治疗计划的剂量分布。将植入物插入模拟椎骨的体模中,并在体模上创建容积调强弧形治疗(VMAT)计划,以单次分割方式向靶区给予16 Gy的辐射剂量。每次照射时均进行传输EPID测量。使用伽马分析方法将结果与治疗计划系统进行比较。根据伽马分析结果,未植入模型以95.4%的通过率符合验收标准,而植入模型的通过率在70%至73%之间,未通过测试。此外,未植入模型在等中心处的剂量差异为1.3%,而在植入模型中该差异为7%至8%。我们的研究表明,EPID可用于VMAT-SBRT应用的传输剂量测定。然而,在植入物患者的VMAT-SBRT应用中,通过传输EPID剂量测定法获得了不可接受的剂量差异。在治疗此类患者时,应优先选择能够防止植入物与辐射相互作用的替代治疗方法。

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