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大鼠幼龄和成年后显微动脉吻合术:一项发展与比较研究。

Microsurgical arterial anastomosis in young and adult rats: an evolutive and comparative study.

机构信息

PhD. Universidade de São Paulo - Medical School - Pediatric Liver Transplantation Unit and Laboratory of Research in Pediatric Surgery - Pediatric Surgery Division - São Paulo (SP), Brazil.

Associate professor. Universidade de São Paulo - Medical School - Pediatric Liver Transplantation Unit and Laboratory of Research in Pediatric Surgery - Pediatric Surgery Division - São Paulo (SP), Brazil.

出版信息

Acta Cir Bras. 2022 Sep 5;37(6):e370604. doi: 10.1590/acb370604. eCollection 2022.

Abstract

PURPOSE

To evaluate the caliber of an arterial micro-anastomosis in the young growing animal using a continuous suture technique. Additionally, late morphological changes and blood flows distal to the anastomosis were evaluated.

METHODS

Seventy-four Wistar rats were submitted to laparotomy to access the aorta for blood flow measurement. The aorta was sectioned using microsurgery technique and an end-to-end anastomosis with continuous suture. After a period of six months to one year, the anastomosis was checked.

RESULTS

Regarding the size of the aortas, comparing the pre- and postoperative values, there was an increase of 13.33% in adult animals and 25% in young animals, without any difference in the blood flows.

CONCLUSIONS

The arteries of young rats show signs of growth at the site of the anastomosis performed with continuous suture.

摘要

目的

使用连续缝合技术评估年轻生长中的动物的动脉微血管吻合的口径。此外,还评估了吻合口远端的晚期形态变化和血流情况。

方法

74 只 Wistar 大鼠接受剖腹手术以测量主动脉的血流量。使用显微外科技术将主动脉切开,然后进行端端吻合的连续缝合。6 个月至 1 年后,检查吻合口。

结果

就主动脉的大小而言,与术前和术后值相比,成年动物增加了 13.33%,而幼年动物增加了 25%,但血流量没有差异。

结论

使用连续缝合进行吻合的幼年大鼠的动脉在吻合部位显示出生长迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91a4/9448246/23e16a137db8/1678-2674-acb-37-6-e370604-gf01.jpg

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