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由感染利什曼原虫(Leishmania)引起的内脏利什曼病(利什曼原虫)与霍奇金淋巴瘤相关。

Visceral leishmaniasis caused by Leishmania (Leishmania) amazonensis associated with Hodgkin's lymphoma.

机构信息

Universidade de São Paulo, Faculdade de Medicina, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil.

Universidade de São Paulo, Faculdade de Medicina, Instituto de Medicina Tropical de São Paulo, Laboratório de Protozoologia (LIM 49), São Paulo, São Paulo, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2022 Sep 5;64:e51. doi: 10.1590/S1678-9946202264051. eCollection 2022.

Abstract

Visceral leishmaniasis (VL) is mainly caused by Leishmania (Leishmania) donovani and Leishmania (L.) infantum; however, other Leishmania species have been associated with VL. We report a case of a patient simultaneously diagnosed with VL caused by Leishmania (L.) amazonensis and Hodgkin's lymphoma. After treatment with liposomal amphotericin B and chemotherapy, the patient presented a clinical cure. This case report reinforces the hypothesis that other Leishmania species can cause visceral lesions mainly related to immunosuppression.

摘要

内脏利什曼病(VL)主要由利什曼原虫(Leishmania)引起。然而,其他利什曼原虫物种也与 VL 相关。我们报告了一例同时诊断为由利什曼原虫(L.)引起的 VL 和霍奇金淋巴瘤的患者。在接受脂质体两性霉素 B 和化疗治疗后,患者临床治愈。本病例报告加强了其他利什曼原虫物种可引起主要与免疫抑制相关的内脏病变的假说。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9740/9448255/c3fde2f9381d/1678-9946-rimtsp-64-S1678-9946202264051-gf01.jpg

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